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Development of functionally selective, small molecule agonists at kappa opioid receptors.
Zhou L, Lovell KM, Frankowski KJ, Slauson SR, Phillips AM, Streicher JM, Stahl E, Schmid CL, Hodder P, Madoux F, Cameron MD, Prisinzano TE, Aubé J, Bohn LM. Zhou L, et al. Among authors: prisinzano te. J Biol Chem. 2013 Dec 20;288(51):36703-16. doi: 10.1074/jbc.M113.504381. Epub 2013 Nov 1. J Biol Chem. 2013. PMID: 24187130 Free PMC article.
Structure-activity relationship studies of functionally selective kappa opioid receptor agonists that modulate ERK 1/2 phosphorylation while preserving G protein over βarrestin2 signaling bias.
Lovell KM, Frankowski KJ, Stahl EL, Slauson SR, Yoo E, Prisinzano TE, Aubé J, Bohn LM. Lovell KM, et al. Among authors: prisinzano te. ACS Chem Neurosci. 2015 Aug 19;6(8):1411-9. doi: 10.1021/acschemneuro.5b00092. Epub 2015 May 1. ACS Chem Neurosci. 2015. PMID: 25891774 Free PMC article.
Semisynthetic neoclerodanes as kappa opioid receptor probes.
Lovell KM, Vasiljevik T, Araya JJ, Lozama A, Prevatt-Smith KM, Day VW, Dersch CM, Rothman RB, Butelman ER, Kreek MJ, Prisinzano TE. Lovell KM, et al. Among authors: prisinzano te. Bioorg Med Chem. 2012 May 1;20(9):3100-10. doi: 10.1016/j.bmc.2012.02.040. Epub 2012 Mar 1. Bioorg Med Chem. 2012. PMID: 22464684 Free PMC article.
LC-MS/MS quantification of salvinorin A from biological fluids.
Caspers MJ, Williams TD, Lovell KM, Lozama A, Butelman ER, Kreek MJ, Johnson M, Griffiths R, Maclean K, Prisinzano TE. Caspers MJ, et al. Among authors: prisinzano te. Anal Methods. 2013 Dec 21;5(24):10.1039/C3AY40810H. doi: 10.1039/C3AY40810H. Anal Methods. 2013. PMID: 24416081 Free PMC article.
167 results