Chen R - Search Results

1

The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.

Zhu H, Woolfenden S, Bronson RT, Jaffer ZM, Barluenga S, Winssinger N, Rubenstein AE, Chen R, Charest A. Zhu H, et al. Among authors: chen r. Mol Cancer Ther. 2010 Sep;9(9):2618-26. doi: 10.1158/1535-7163.MCT-10-0248. Epub 2010 Jul 19. Mol Cancer Ther. 2010. PMID: 20643786 Free PMC article.

2

Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.

Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. Tanaka K, et al. Among authors: chen r. Clin Cancer Res. 2013 Jul 15;19(14):3856-70. doi: 10.1158/1078-0432.CCR-12-3167. Epub 2013 May 28. Clin Cancer Res. 2013. PMID: 23714726 Free PMC article.

3

A novel small molecule HSP90 inhibitor, NXD30001, differentially induces heat shock proteins in nervous tissue in culture and in vivo.

Cha JR, St Louis KJ, Tradewell ML, Gentil BJ, Minotti S, Jaffer ZM, Chen R, Rubenstein AE, Durham HD. Cha JR, et al. Among authors: chen r. Cell Stress Chaperones. 2014 May;19(3):421-35. doi: 10.1007/s12192-013-0467-2. Epub 2013 Oct 3. Cell Stress Chaperones. 2014. PMID: 24092395 Free PMC article.

4

Synthesis of pochoxime prodrugs as potent HSP90 inhibitors.

Wang C, Barluenga S, Koripelly GK, Fontaine JG, Chen R, Yu JC, Shen X, Chabala JC, Heck JV, Rubenstein A, Winssinger N. Wang C, et al. Among authors: chen r. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3836-40. doi: 10.1016/j.bmcl.2009.04.030. Epub 2009 Apr 17. Bioorg Med Chem Lett. 2009. PMID: 19410458

5

Inhibition of HSP90 with pochoximes: SAR and structure-based insights.

Barluenga S, Fontaine JG, Wang C, Aouadi K, Chen R, Beebe K, Neckers L, Winssinger N. Barluenga S, et al. Among authors: chen r. Chembiochem. 2009 Nov 23;10(17):2753-9. doi: 10.1002/cbic.200900494. Chembiochem. 2009. PMID: 19856365 Free PMC article.

6

Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2.

Evans DG, Kalamarides M, Hunter-Schaedle K, Blakeley J, Allen J, Babovic-Vuskanovic D, Belzberg A, Bollag G, Chen R, DiTomaso E, Golfinos J, Harris G, Jacob A, Kalpana G, Karajannis M, Korf B, Kurzrock R, Law M, McClatchey A, Packer R, Roehm P, Rubenstein A, Slattery W 3rd, Tonsgard JH, Welling DB, Widemann B, Yohay K, Giovannini M. Evans DG, et al. Among authors: chen r. Clin Cancer Res. 2009 Aug 15;15(16):5032-5039. doi: 10.1158/1078-0432.CCR-08-3011. Epub 2009 Aug 11. Clin Cancer Res. 2009. PMID: 19671848 Free PMC article.

7

Graves' disease diagnosed nearly six months after microwave ablation of benign thyroid nodules: a case report.

Gu Y, Chen R, Chen M, Jiang X, Wang L, Huang X. Gu Y, et al. Among authors: chen r. BMC Endocr Disord. 2025 Jan 6;25(1):5. doi: 10.1186/s12902-024-01824-w. BMC Endocr Disord. 2025. PMID: 39762840

8

Identifying Predictors of Spatiotemporal Variations in Residential Radon Concentrations across North Carolina Using Machine Learning Analytics.

Yang Z, Prox L, Meernik C, Raveendran Y, Press D, Gibson P, Koch A, Ajumobi O, Clarke J, Chen R, Zhang JJ, Akinyemiju T. Yang Z, et al. Among authors: chen r. Environ Pollut. 2025 Jan 4:125592. doi: 10.1016/j.envpol.2024.125592. Online ahead of print. Environ Pollut. 2025. PMID: 39761718

9

PPI-CoAttNet: A Web Server for Protein-Protein Interaction Tasks Using a Coattention Model.

Bian Q, Shen Z, Gao J, Shen L, Lu Y, Zhang Q, Chen R, Xu D, Liu T, Che J, Lu Y, Dong X. Bian Q, et al. Among authors: chen r. J Chem Inf Model. 2025 Jan 6. doi: 10.1021/acs.jcim.4c01365. Online ahead of print. J Chem Inf Model. 2025. PMID: 39761551

10

Comparative study on the reaction mechanism of 5-hydroxymethyl furfural on Pd(111) and Cu(111).

Gao Y, Liu FF, Wang H, Xu K, Chen R, Zhang W, Shi Y. Gao Y, et al. Among authors: chen r. J Mol Model. 2025 Jan 6;31(1):34. doi: 10.1007/s00894-024-06267-7. J Mol Model. 2025. PMID: 39760759

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