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Species-specific inflammatory responses as a primary component for the development of glomerular lesions in mice and monkeys following chronic administration of a second-generation antisense oligonucleotide.
Frazier KS, Sobry C, Derr V, Adams MJ, Besten CD, De Kimpe S, Francis I, Gales TL, Haworth R, Maguire SR, Mirabile RC, Mullins D, Palate B, Doorten YP, Ridings JE, Scicchitano MS, Silvano J, Woodfine J. Frazier KS, et al. Among authors: francis i. Toxicol Pathol. 2014 Jul;42(5):923-35. doi: 10.1177/0192623313505781. Epub 2013 Nov 28. Toxicol Pathol. 2014. PMID: 24292388
Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury.
Swain A, Turton J, Scudamore C, Maguire D, Pereira I, Freitas S, Smyth R, Munday M, Stamp C, Gandhi M, Sondh S, Ashall H, Francis I, Woodfine J, Bowles J, York M. Swain A, et al. Among authors: francis i. J Appl Toxicol. 2012 Jun;32(6):417-28. doi: 10.1002/jat.1727. Epub 2011 Sep 8. J Appl Toxicol. 2012. PMID: 21905055
Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress.
O'Brien KA, McNally BD, Sowton AP, Murgia A, Armitage J, Thomas LW, Krause FN, Maddalena LA, Francis I, Kavanagh S, Williams DP, Ashcroft M, Griffin JL, Lyon JJ, Murray AJ. O'Brien KA, et al. Among authors: francis i. BMC Biol. 2021 Dec 15;19(1):265. doi: 10.1186/s12915-021-01192-0. BMC Biol. 2021. PMID: 34911556 Free PMC article.
840 results