Testa JR - Search Results

1

Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.

Tan Y, You H, Coffey FJ, Wiest DL, Testa JR. Tan Y, et al. Among authors: testa jr. Genesis. 2010 Sep;48(9):531-9. doi: 10.1002/dvg.20657. Genesis. 2010. PMID: 20665729 Free PMC article.

2

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.

Altomare DA, You H, Xiao GH, Ramos-Nino ME, Skele KL, De Rienzo A, Jhanwar SC, Mossman BT, Kane AB, Testa JR. Altomare DA, et al. Among authors: testa jr. Oncogene. 2005 Sep 8;24(40):6080-9. doi: 10.1038/sj.onc.1208744. Oncogene. 2005. PMID: 15897870

3

AKT signaling in normal and malignant cells.

Testa JR, Tsichlis PN. Testa JR, et al. Oncogene. 2005 Nov 14;24(50):7391-3. doi: 10.1038/sj.onc.1209100. Oncogene. 2005. PMID: 16288285

4

Perturbations of the AKT signaling pathway in human cancer.

Altomare DA, Testa JR. Altomare DA, et al. Among authors: testa jr. Oncogene. 2005 Nov 14;24(50):7455-64. doi: 10.1038/sj.onc.1209085. Oncogene. 2005. PMID: 16288292 Review.

5

A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice.

Tan Y, Timakhov RA, Rao M, Altomare DA, Xu J, Liu Z, Gao Q, Jhanwar SC, Di Cristofano A, Wiest DL, Knepper JE, Testa JR. Tan Y, et al. Among authors: testa jr. Cancer Res. 2008 Mar 1;68(5):1296-302. doi: 10.1158/0008-5472.CAN-07-3218. Cancer Res. 2008. PMID: 18316591

6

Recurrent chromosomal rearrangements implicate oncogenes contributing to T-cell lymphomagenesis in Lck-MyrAkt2 transgenic mice.

Timakhov RA, Tan Y, Rao M, Liu Z, Altomare DA, Pei J, Wiest DL, Favorova OO, Knepper JE, Testa JR. Timakhov RA, et al. Among authors: testa jr. Genes Chromosomes Cancer. 2009 Sep;48(9):786-94. doi: 10.1002/gcc.20683. Genes Chromosomes Cancer. 2009. PMID: 19530243 Free PMC article.

7

Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.

Tan Y, You H, Wu C, Altomare DA, Testa JR. Tan Y, et al. Among authors: testa jr. J Biol Chem. 2010 Feb 26;285(9):6377-89. doi: 10.1074/jbc.M109.068452. Epub 2009 Dec 29. J Biol Chem. 2010. PMID: 20040596 Free PMC article.

8

Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling.

Tan Y, Cheung M, Pei J, Menges CW, Godwin AK, Testa JR. Tan Y, et al. Among authors: testa jr. Cancer Res. 2010 Nov 15;70(22):9197-206. doi: 10.1158/0008-5472.CAN-10-1568. Epub 2010 Nov 2. Cancer Res. 2010. PMID: 21045156 Free PMC article.

9

Germline BAP1 mutations predispose to malignant mesothelioma.

Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M. Testa JR, et al. Nat Genet. 2011 Aug 28;43(10):1022-5. doi: 10.1038/ng.912. Nat Genet. 2011. PMID: 21874000 Free PMC article.

10

CD45-deficient severe combined immunodeficiency caused by uniparental disomy.

Roberts JL, Buckley RH, Luo B, Pei J, Lapidus A, Peri S, Wei Q, Shin J, Parrott RE, Dunbrack RL Jr, Testa JR, Zhong XP, Wiest DL. Roberts JL, et al. Among authors: testa jr. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10456-61. doi: 10.1073/pnas.1202249109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689986 Free PMC article.

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