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Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.
Seubert A, Calabro S, Santini L, Galli B, Genovese A, Valentini S, Aprea S, Colaprico A, D'Oro U, Giuliani MM, Pallaoro M, Pizza M, O'Hagan DT, Wack A, Rappuoli R, De Gregorio E. Seubert A, et al. Among authors: giuliani mm. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11169-74. doi: 10.1073/pnas.1107941108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690334 Free PMC article.
Rational design of a meningococcal antigen inducing broad protective immunity.
Scarselli M, Aricò B, Brunelli B, Savino S, Di Marcello F, Palumbo E, Veggi D, Ciucchi L, Cartocci E, Bottomley MJ, Malito E, Lo Surdo P, Comanducci M, Giuliani MM, Cantini F, Dragonetti S, Colaprico A, Doro F, Giannetti P, Pallaoro M, Brogioni B, Tontini M, Hilleringmann M, Nardi-Dei V, Banci L, Pizza M, Rappuoli R. Scarselli M, et al. Among authors: giuliani mm. Sci Transl Med. 2011 Jul 13;3(91):91ra62. doi: 10.1126/scitranslmed.3002234. Sci Transl Med. 2011. PMID: 21753121
RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies.
Harfouche C, Filippini S, Gianfaldoni C, Ruggiero P, Moschioni M, Maccari S, Pancotto L, Arcidiacono L, Galletti B, Censini S, Mori E, Giuliani M, Facciotti C, Cartocci E, Savino S, Doro F, Pallaoro M, Nocadello S, Mancuso G, Haston M, Goldblatt D, Barocchi MA, Pizza M, Rappuoli R, Masignani V. Harfouche C, et al. Among authors: giuliani m. Infect Immun. 2012 Jan;80(1):451-60. doi: 10.1128/IAI.05780-11. Epub 2011 Nov 14. Infect Immun. 2012. PMID: 22083702 Free PMC article.
A universal vaccine for serogroup B meningococcus.
Giuliani MM, Adu-Bobie J, Comanducci M, Aricò B, Savino S, Santini L, Brunelli B, Bambini S, Biolchi A, Capecchi B, Cartocci E, Ciucchi L, Di Marcello F, Ferlicca F, Galli B, Luzzi E, Masignani V, Serruto D, Veggi D, Contorni M, Morandi M, Bartalesi A, Cinotti V, Mannucci D, Titta F, Ovidi E, Welsch JA, Granoff D, Rappuoli R, Pizza M. Giuliani MM, et al. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10834-9. doi: 10.1073/pnas.0603940103. Epub 2006 Jul 6. Proc Natl Acad Sci U S A. 2006. PMID: 16825336 Free PMC article.
Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines.
Donnelly J, Medini D, Boccadifuoco G, Biolchi A, Ward J, Frasch C, Moxon ER, Stella M, Comanducci M, Bambini S, Muzzi A, Andrews W, Chen J, Santos G, Santini L, Boucher P, Serruto D, Pizza M, Rappuoli R, Giuliani MM. Donnelly J, et al. Among authors: giuliani mm. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19490-5. doi: 10.1073/pnas.1013758107. Epub 2010 Oct 20. Proc Natl Acad Sci U S A. 2010. PMID: 20962280 Free PMC article.
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans.
Serruto D, Spadafina T, Ciucchi L, Lewis LA, Ram S, Tontini M, Santini L, Biolchi A, Seib KL, Giuliani MM, Donnelly JJ, Berti F, Savino S, Scarselli M, Costantino P, Kroll JS, O'Dwyer C, Qiu J, Plaut AG, Moxon R, Rappuoli R, Pizza M, Aricò B. Serruto D, et al. Among authors: giuliani mm. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3770-5. doi: 10.1073/pnas.0915162107. Epub 2010 Feb 3. Proc Natl Acad Sci U S A. 2010. PMID: 20133713 Free PMC article.
869 results