Khadka DB - Search Results

1

Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents.

Yang SH, Van HT, Le TN, Khadka DB, Cho SH, Lee KT, Chung HJ, Lee SK, Ahn CH, Lee YB, Cho WJ. Yang SH, et al. Among authors: khadka db. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5277-81. doi: 10.1016/j.bmcl.2010.06.132. Epub 2010 Jul 3. Bioorg Med Chem Lett. 2010. PMID: 20667733

2

Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA.

Yang SH, Van HT, Le TN, Khadka DB, Cho SH, Lee KT, Lee ES, Lee YB, Ahn CH, Cho WJ. Yang SH, et al. Among authors: khadka db. Eur J Med Chem. 2010 Nov;45(11):5493-7. doi: 10.1016/j.ejmech.2010.08.042. Epub 2010 Aug 24. Eur J Med Chem. 2010. PMID: 20817330

3

3-Arylisoquinolines as novel topoisomerase I inhibitors.

Khadka DB, Cho WJ. Khadka DB, et al. Bioorg Med Chem. 2011 Jan 15;19(2):724-34. doi: 10.1016/j.bmc.2010.10.057. Epub 2010 Nov 2. Bioorg Med Chem. 2011. PMID: 21095131 Review.

4

Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors.

Yang SH, Khadka DB, Cho SH, Ju HK, Lee KY, Han HJ, Lee KT, Cho WJ. Yang SH, et al. Among authors: khadka db. Bioorg Med Chem. 2011 Jan 15;19(2):968-77. doi: 10.1016/j.bmc.2010.11.057. Epub 2010 Nov 30. Bioorg Med Chem. 2011. PMID: 21185195

5

Design, synthesis and docking study of 5-amino substituted indeno[1,2-c]isoquinolines as novel topoisomerase I inhibitors.

Khadka DB, Le QM, Yang SH, Van HT, Le TN, Cho SH, Kwon Y, Lee KT, Lee ES, Cho WJ. Khadka DB, et al. Bioorg Med Chem. 2011 Mar 15;19(6):1924-9. doi: 10.1016/j.bmc.2011.01.064. Epub 2011 Feb 3. Bioorg Med Chem. 2011. PMID: 21353568

6

Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling.

Le TN, Yang SH, Khadka DB, Van HT, Cho SH, Kwon Y, Lee ES, Lee KT, Cho WJ. Le TN, et al. Among authors: khadka db. Bioorg Med Chem. 2011 Jul 15;19(14):4399-404. doi: 10.1016/j.bmc.2011.05.012. Epub 2011 May 20. Bioorg Med Chem. 2011. PMID: 21684168

7

Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study.

Van HT, Khadka DB, Yang SH, Le TN, Cho SH, Zhao C, Lee IS, Kwon Y, Lee KT, Kim YC, Cho WJ. Van HT, et al. Among authors: khadka db. Bioorg Med Chem. 2011 Sep 15;19(18):5311-20. doi: 10.1016/j.bmc.2011.08.006. Epub 2011 Aug 8. Bioorg Med Chem. 2011. PMID: 21873069

8

Application of ring-closing metathesis for the synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones.

Van HT, Khadka DB, Le TN, Yang SH, Cho WJ. Van HT, et al. Among authors: khadka db. Chem Pharm Bull (Tokyo). 2011;59(9):1169-73. doi: 10.1248/cpb.59.1169. Chem Pharm Bull (Tokyo). 2011. PMID: 21881264 Free article.

9

Structure-based virtual screening and identification of a novel androgen receptor antagonist.

Song CH, Yang SH, Park E, Cho SH, Gong EY, Khadka DB, Cho WJ, Lee K. Song CH, et al. Among authors: khadka db. J Biol Chem. 2012 Aug 31;287(36):30769-80. doi: 10.1074/jbc.M112.379107. Epub 2012 Jul 13. J Biol Chem. 2012. PMID: 22798067 Free PMC article.

10

SAR based design of nicotinamides as a novel class of androgen receptor antagonists for prostate cancer.

Yang SH, Song CH, Van HT, Park E, Khadka DB, Gong EY, Lee K, Cho WJ. Yang SH, et al. Among authors: khadka db. J Med Chem. 2013 Apr 25;56(8):3414-8. doi: 10.1021/jm3014103. Epub 2013 Apr 5. J Med Chem. 2013. PMID: 23527816

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