Ghosh I - Search Results

1

A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases.

Jester BW, Cox KJ, Gaj A, Shomin CD, Porter JR, Ghosh I. Jester BW, et al. Among authors: ghosh i. J Am Chem Soc. 2010 Aug 25;132(33):11727-35. doi: 10.1021/ja104491h. J Am Chem Soc. 2010. PMID: 20669947 Free PMC article.

2

Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A.

Meyer SC, Shomin CD, Gaj T, Ghosh I. Meyer SC, et al. Among authors: ghosh i. J Am Chem Soc. 2007 Nov 14;129(45):13812-3. doi: 10.1021/ja076197d. Epub 2007 Oct 18. J Am Chem Soc. 2007. PMID: 17944472 No abstract available.

3

A general and rapid cell-free approach for the interrogation of protein-protein, protein-DNA, and protein-RNA interactions and their antagonists utilizing split-protein reporters.

Porter JR, Stains CI, Jester BW, Ghosh I. Porter JR, et al. Among authors: ghosh i. J Am Chem Soc. 2008 May 21;130(20):6488-97. doi: 10.1021/ja7114579. Epub 2008 Apr 29. J Am Chem Soc. 2008. PMID: 18444624

4

Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling.

Shomin CD, Meyer SC, Ghosh I. Shomin CD, et al. Among authors: ghosh i. Bioorg Med Chem. 2009 Sep 1;17(17):6196-202. doi: 10.1016/j.bmc.2009.07.056. Epub 2009 Jul 26. Bioorg Med Chem. 2009. PMID: 19674907 Free PMC article.

5

An autoinhibited coiled-coil design strategy for split-protein protease sensors.

Shekhawat SS, Porter JR, Sriprasad A, Ghosh I. Shekhawat SS, et al. Among authors: ghosh i. J Am Chem Soc. 2009 Oct 28;131(42):15284-90. doi: 10.1021/ja9050857. J Am Chem Soc. 2009. PMID: 19803505 Free PMC article.

6

Toward a general approach for RNA-templated hierarchical assembly of split-proteins.

Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. Among authors: ghosh i. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.

7

Tinkering outside the kinase ATP box: allosteric (type IV) and bivalent (type V) inhibitors of protein kinases.

Cox KJ, Shomin CD, Ghosh I. Cox KJ, et al. Among authors: ghosh i. Future Med Chem. 2011 Jan;3(1):29-43. doi: 10.4155/fmc.10.272. Future Med Chem. 2011. PMID: 21428824 Review.

8

Selection of cyclic-peptide inhibitors targeting Aurora kinase A: problems and solutions.

Shomin CD, Restituyo E, Cox KJ, Ghosh I. Shomin CD, et al. Among authors: ghosh i. Bioorg Med Chem. 2011 Nov 15;19(22):6743-9. doi: 10.1016/j.bmc.2011.09.049. Epub 2011 Sep 29. Bioorg Med Chem. 2011. PMID: 22004849 Free PMC article.

9

Testing the promiscuity of commercial kinase inhibitors against the AGC kinase group using a split-luciferase screen.

Jester BW, Gaj A, Shomin CD, Cox KJ, Ghosh I. Jester BW, et al. Among authors: ghosh i. J Med Chem. 2012 Feb 23;55(4):1526-37. doi: 10.1021/jm201265f. Epub 2012 Feb 10. J Med Chem. 2012. PMID: 22257127 Free PMC article.

10

DNA sequence-enabled reassembly of the green fluorescent protein.

Stains CI, Porter JR, Ooi AT, Segal DJ, Ghosh I. Stains CI, et al. Among authors: ghosh i. J Am Chem Soc. 2005 Aug 10;127(31):10782-3. doi: 10.1021/ja051969w. J Am Chem Soc. 2005. PMID: 16076155

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