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Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.
Li C, Chen P, Palladino A, Narayan S, Russell LK, Sayed S, Xiong G, Chen J, Stokes D, Butt YM, Jones PM, Collins HW, Cohen NA, Cohen AS, Nissim I, Smith TJ, Strauss AW, Matschinsky FM, Bennett MJ, Stanley CA. Li C, et al. Among authors: matschinsky fm. J Biol Chem. 2010 Oct 8;285(41):31806-18. doi: 10.1074/jbc.M110.123638. Epub 2010 Jul 29. J Biol Chem. 2010. PMID: 20670938 Free PMC article.
A signaling role of glutamine in insulin secretion.
Li C, Buettger C, Kwagh J, Matter A, Daikhin Y, Nissim IB, Collins HW, Yudkoff M, Stanley CA, Matschinsky FM. Li C, et al. Among authors: matschinsky fm. J Biol Chem. 2004 Apr 2;279(14):13393-401. doi: 10.1074/jbc.M311502200. Epub 2004 Jan 20. J Biol Chem. 2004. PMID: 14736887 Free article.
Elimination of KATP channels in mouse islets results in elevated [U-13C]glucose metabolism, glutaminolysis, and pyruvate cycling but a decreased gamma-aminobutyric acid shunt.
Li C, Nissim I, Chen P, Buettger C, Najafi H, Daikhin Y, Nissim I, Collins HW, Yudkoff M, Stanley CA, Matschinsky FM. Li C, et al. Among authors: matschinsky fm. J Biol Chem. 2008 Jun 20;283(25):17238-49. doi: 10.1074/jbc.M709235200. Epub 2008 Apr 29. J Biol Chem. 2008. PMID: 18445600 Free PMC article.
278 results