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Discovery of a novel class of triazolones as checkpoint kinase inhibitors--hit to lead exploration.
Oza V, Ashwell S, Brassil P, Breed J, Deng C, Ezhuthachan J, Haye H, Horn C, Janetka J, Lyne P, Newcombe N, Otterbien L, Pass M, Read J, Roswell S, Su M, Toader D, Yu D, Yu Y, Valentine A, Webborn P, White A, Zabludoff S, Zheng X. Oza V, et al. Among authors: white a. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5133-8. doi: 10.1016/j.bmcl.2010.07.015. Epub 2010 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 20673630
AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies.
Zabludoff SD, Deng C, Grondine MR, Sheehy AM, Ashwell S, Caleb BL, Green S, Haye HR, Horn CL, Janetka JW, Liu D, Mouchet E, Ready S, Rosenthal JL, Queva C, Schwartz GK, Taylor KJ, Tse AN, Walker GE, White AM. Zabludoff SD, et al. Mol Cancer Ther. 2008 Sep;7(9):2955-66. doi: 10.1158/1535-7163.MCT-08-0492. Mol Cancer Ther. 2008. PMID: 18790776
The long way from raw data to NAM-based information: Overview on data layers and processing steps.
Blum J, Brüll M, Hengstler JG, Dietrich DR, Gruber AJ, Dipalo M, Kraushaar U, Mangas I, Terron A, Fritsche E, Marx-Stoelting P, Hardy B, Schepky A, Escher S, Hartung T, Landsiedel R, Odermatt A, Sachana M, Koch K, Dönmez A, Masjosthusmann S, Bothe K, Schildknecht S, Beilmann M, Beltman JB, Fitzpatrick S, Mangerich A, Rehm M, Tangianu S, Zickgraf FM, Kamp H, Burger G, van de Water B, Kleinstreuer N, White A, Leist M. Blum J, et al. Among authors: white a. ALTEX. 2025;42(1):167-180. doi: 10.14573/altex.2412171. ALTEX. 2025. PMID: 39817434 Free article.
Two-stage revision anterior cruciate ligament reconstruction reduces failure risk but leads to lesser clinical outcomes than single-stage revision after primary anterior cruciate ligament graft failure: a retrospective cohort study.
Ifarraguerri AM, Graham GD, White AB, Berk AN, Gachigi KK, Siparsky PN, Trofa DP, Piasecki DP, Fleischli JE, Saltzman BM. Ifarraguerri AM, et al. Among authors: white ab. Knee Surg Relat Res. 2025 Jan 15;37(1):5. doi: 10.1186/s43019-024-00257-y. Knee Surg Relat Res. 2025. PMID: 39815325 Free PMC article.
7,065 results