Pei G - Search Results

1

Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents.

Li B, Jones ED, Zhou E, Chen L, Baylis DC, Yu S, Wang M, He X, Coates JA, Rhodes DI, Pei G, Deadman JJ, Xie X, Ma D. Li B, et al. Among authors: pei g. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5334-6. doi: 10.1016/j.bmcl.2010.05.046. Epub 2010 May 19. Bioorg Med Chem Lett. 2010. PMID: 20674358

2

Human mu-opioid receptor overexpressed in Sf9 insect cells functionally coupled to endogenous Gi/o proteins.

Wei Q, Zhou DH, Shen QX, Chen J, Chen LW, Wang TL, Pei G, Chi ZQ. Wei Q, et al. Among authors: pei g. Cell Res. 2000 Jun;10(2):93-102. doi: 10.1038/sj.cr.7290039. Cell Res. 2000. PMID: 10896171

3

Elucidating the inhibiting mode of AHPBA derivatives against HIV-1 protease and building predictive 3D-QSAR models.

Huang X, Xu L, Luo X, Fan K, Ji R, Pei G, Chen K, Jiang H. Huang X, et al. Among authors: pei g. J Med Chem. 2002 Jan 17;45(2):333-43. doi: 10.1021/jm0102710. J Med Chem. 2002. PMID: 11784138

4

An overall picture of chemokine receptors: basic research and drug development.

Chen L, Pei G, Zhang W. Chen L, et al. Among authors: pei g. Curr Pharm Des. 2004;10(9):1045-55. doi: 10.2174/1381612043452749. Curr Pharm Des. 2004. PMID: 15078132 Review.

5

Synthesis and biological evaluation of 1,3,3,4-tetrasubstituted pyrrolidine CCR5 receptor antagonists. Discovery of a potent and orally bioavailable anti-HIV agent.

Ma D, Yu S, Li B, Chen L, Chen R, Yu K, Zhang L, Chen Z, Zhong D, Gong Z, Wang R, Jiang H, Pei G. Ma D, et al. Among authors: pei g. ChemMedChem. 2007 Feb;2(2):187-93. doi: 10.1002/cmdc.200600182. ChemMedChem. 2007. PMID: 17163560

6

Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 1: Tuning the N-substituents.

Ben L, Jones ED, Zhou E, Li C, Baylis DC, Yu S, Wang M, He X, Coates JA, Rhodes DI, Pei G, Deadman JJ, Xie X, Ma D. Ben L, et al. Among authors: pei g. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4012-4. doi: 10.1016/j.bmcl.2010.05.102. Epub 2010 Jun 1. Bioorg Med Chem Lett. 2010. PMID: 20561788

7

Targeting the γ-/β-secretase interaction reduces β-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis.

Cui J, Wang X, Li X, Wang X, Zhang C, Li W, Zhang Y, Gu H, Xie X, Nan F, Zhao J, Pei G. Cui J, et al. Among authors: pei g. Cell Discov. 2015 Aug 18;1:15021. doi: 10.1038/celldisc.2015.21. eCollection 2015. Cell Discov. 2015. PMID: 27462420 Free PMC article.

8

WGCNA Application to Proteomic and Metabolomic Data Analysis.

Pei G, Chen L, Zhang W. Pei G, et al. Methods Enzymol. 2017;585:135-158. doi: 10.1016/bs.mie.2016.09.016. Epub 2016 Dec 15. Methods Enzymol. 2017. PMID: 28109426

9

Differential efficacies of kappa agonists to induce homologous desensitization of human kappa opioid receptor.

Ling K, Ma L, Pei G. Ling K, et al. Among authors: pei g. Neurosci Lett. 1998 Jan 2;240(1):25-8. doi: 10.1016/s0304-3940(97)00921-x. Neurosci Lett. 1998. PMID: 9488166

10

Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization.

Zhao J, Ma L, Wu YL, Wang P, Hu W, Pei G. Zhao J, et al. Among authors: pei g. J Cell Biochem. 1998 Oct 1;71(1):36-45. doi: 10.1002/(sici)1097-4644(19981001)71:1<36::aid-jcb4>3.0.co;2-2. J Cell Biochem. 1998. PMID: 9736452

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