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148 results

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Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
Ginn JD, Bosanac T, Chen R, Cywin C, Hickey E, Kashem M, Kerr S, Kugler S, Li X, Prokopowicz A 3rd, Schlyer S, Smith JD, Turner MR, Wu F, Young ER. Ginn JD, et al. Among authors: young er. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5153-6. doi: 10.1016/j.bmcl.2010.07.014. Epub 2010 Aug 1. Bioorg Med Chem Lett. 2010. PMID: 20678931
Discovery of potent and selective PKC-theta inhibitors.
Cywin CL, Dahmann G, Prokopowicz AS 3rd, Young ER, Magolda RL, Cardozo MG, Cogan DA, Disalvo D, Ginn JD, Kashem MA, Wolak JP, Homon CA, Farrell TM, Grbic H, Hu H, Kaplita PV, Liu LH, Spero DM, Jeanfavre DD, O'Shea KM, White DM, Woska JR Jr, Brown ML. Cywin CL, et al. Among authors: young er. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30. doi: 10.1016/j.bmcl.2006.09.056. Epub 2006 Oct 19. Bioorg Med Chem Lett. 2007. PMID: 17055721
Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors.
Bekkali Y, Thomson DS, Betageri R, Emmanuel MJ, Hao MH, Hickey E, Liu W, Patel U, Ward YD, Young ER, Nelson R, Kukulka A, Brown ML, Crane K, White D, Freeman DM, Labadia ME, Wildeson J, Spero DM. Bekkali Y, et al. Among authors: young er. Bioorg Med Chem Lett. 2007 May 1;17(9):2465-9. doi: 10.1016/j.bmcl.2007.02.046. Epub 2007 Feb 23. Bioorg Med Chem Lett. 2007. PMID: 17379516
Pinning Down Small Populations of Photoinduced Intermediates Using Transient Absorption Spectroscopy and Time-Dependent Density Functional Theory Difference Spectra to Provide Mechanistic Insight into Controlling Pyridine Azo Dynamics with Protons.
Knepp ZJ, Hamburger RC, Thongchai IA, Englehart K, Sorto K, Jaffer A, Young ER, Fredin LA. Knepp ZJ, et al. Among authors: young er. J Phys Chem Lett. 2024 Sep 26;15(38):9593-9600. doi: 10.1021/acs.jpclett.4c02155. Epub 2024 Sep 13. J Phys Chem Lett. 2024. PMID: 39270049 Free PMC article.
Long guidewire peripheral intravenous catheters in emergency departments for management of difficult intravenous access: A multicenter, pragmatic, randomized controlled trial.
Xu HG, Corley A, Young ER, Doubrovsky A, Ware RS, Afoakwah C, Wang C, Stirling S, Marsh N. Xu HG, et al. Among authors: young er. Acad Emerg Med. 2024 Dec;31(12):1223-1232. doi: 10.1111/acem.15004. Epub 2024 Sep 9. Acad Emerg Med. 2024. PMID: 39248350 Free PMC article. Clinical Trial.
Sutureless vascular anastomotic approaches and their potential impacts.
Ribaudo JG, He K, Madira S, Young ER, Martin C, Lu T, Sacks JM, Li X. Ribaudo JG, et al. Among authors: young er. Bioact Mater. 2024 Apr 23;38:73-94. doi: 10.1016/j.bioactmat.2024.04.003. eCollection 2024 Aug. Bioact Mater. 2024. PMID: 38699240 Free PMC article. Review.
148 results