Borchelt DR - Search Results

1

Aggregation modulating elements in mutant human superoxide dismutase 1.

Karch CM, Borchelt DR. Karch CM, et al. Among authors: borchelt dr. Arch Biochem Biophys. 2010 Nov 15;503(2):175-82. doi: 10.1016/j.abb.2010.07.027. Epub 2010 Aug 2. Arch Biochem Biophys. 2010. PMID: 20682279 Free PMC article.

2

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation.

Wang J, Xu G, Borchelt DR. Wang J, et al. Among authors: borchelt dr. Neurobiol Dis. 2002 Mar;9(2):139-48. doi: 10.1006/nbdi.2001.0471. Neurobiol Dis. 2002. PMID: 11895367

3

Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation.

Wang J, Xu G, Li H, Gonzales V, Fromholt D, Karch C, Copeland NG, Jenkins NA, Borchelt DR. Wang J, et al. Among authors: borchelt dr. Hum Mol Genet. 2005 Aug 15;14(16):2335-47. doi: 10.1093/hmg/ddi236. Epub 2005 Jul 6. Hum Mol Genet. 2005. PMID: 16000321

4

A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis.

Karch CM, Borchelt DR. Karch CM, et al. Among authors: borchelt dr. J Biol Chem. 2008 May 16;283(20):13528-37. doi: 10.1074/jbc.M800564200. Epub 2008 Mar 3. J Biol Chem. 2008. PMID: 18316367 Free PMC article.

5

Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.

Xu G, Karch C, Li N, Lin N, Fromholt D, Gonzales V, Borchelt DR. Xu G, et al. Among authors: borchelt dr. PLoS One. 2008 Sep 8;3(9):e3159. doi: 10.1371/journal.pone.0003159. PLoS One. 2008. PMID: 18776935 Free PMC article.

6

Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme.

Prudencio M, Durazo A, Whitelegge JP, Borchelt DR. Prudencio M, et al. Among authors: borchelt dr. J Neurochem. 2009 Feb;108(4):1009-18. doi: 10.1111/j.1471-4159.2008.05839.x. Epub 2008 Dec 11. J Neurochem. 2009. PMID: 19077113 Free PMC article.

7

Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q.

Winkler DD, Schuermann JP, Cao X, Holloway SP, Borchelt DR, Carroll MC, Proescher JB, Culotta VC, Hart PJ. Winkler DD, et al. Among authors: borchelt dr. Biochemistry. 2009 Apr 21;48(15):3436-47. doi: 10.1021/bi8021735. Biochemistry. 2009. PMID: 19227972 Free PMC article.

8

Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS.

Karch CM, Prudencio M, Winkler DD, Hart PJ, Borchelt DR. Karch CM, et al. Among authors: borchelt dr. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7774-9. doi: 10.1073/pnas.0902505106. Epub 2009 Apr 30. Proc Natl Acad Sci U S A. 2009. PMID: 19416874 Free PMC article.

9

Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease.

Prudencio M, Hart PJ, Borchelt DR, Andersen PM. Prudencio M, et al. Among authors: borchelt dr. Hum Mol Genet. 2009 Sep 1;18(17):3217-26. doi: 10.1093/hmg/ddp260. Epub 2009 May 30. Hum Mol Genet. 2009. PMID: 19483195 Free PMC article.

10

Immature copper-zinc superoxide dismutase and familial amyotrophic lateral sclerosis.

Seetharaman SV, Prudencio M, Karch C, Holloway SP, Borchelt DR, Hart PJ. Seetharaman SV, et al. Among authors: borchelt dr. Exp Biol Med (Maywood). 2009 Oct;234(10):1140-54. doi: 10.3181/0903-MR-104. Epub 2009 Jul 13. Exp Biol Med (Maywood). 2009. PMID: 19596823 Free PMC article. Review.

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