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Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.
Kogan-Sakin I, Tabach Y, Buganim Y, Molchadsky A, Solomon H, Madar S, Kamer I, Stambolsky P, Shelly A, Goldfinger N, Valsesia-Wittmann S, Puisieux A, Zundelevich A, Gal-Yam EN, Avivi C, Barshack I, Brait M, Sidransky D, Domany E, Rotter V. Kogan-Sakin I, et al. Among authors: madar s. Cell Death Differ. 2011 Feb;18(2):271-81. doi: 10.1038/cdd.2010.94. Epub 2010 Aug 6. Cell Death Differ. 2011. PMID: 20689556 Free PMC article.
p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition.
Brosh R, Assia-Alroy Y, Molchadsky A, Bornstein C, Dekel E, Madar S, Shetzer Y, Rivlin N, Goldfinger N, Sarig R, Rotter V. Brosh R, et al. Among authors: madar s. Cell Death Differ. 2013 Feb;20(2):312-20. doi: 10.1038/cdd.2012.125. Epub 2012 Sep 21. Cell Death Differ. 2013. PMID: 22996684 Free PMC article.
Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species.
Kalo E, Kogan-Sakin I, Solomon H, Bar-Nathan E, Shay M, Shetzer Y, Dekel E, Goldfinger N, Buganim Y, Stambolsky P, Goldstein I, Madar S, Rotter V. Kalo E, et al. Among authors: madar s. J Cell Sci. 2012 Nov 15;125(Pt 22):5578-86. doi: 10.1242/jcs.106815. Epub 2012 Aug 16. J Cell Sci. 2012. PMID: 22899716
p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways.
Buganim Y, Solomon H, Rais Y, Kistner D, Nachmany I, Brait M, Madar S, Goldstein I, Kalo E, Adam N, Gordin M, Rivlin N, Kogan I, Brosh R, Sefadia-Elad G, Goldfinger N, Sidransky D, Kloog Y, Rotter V. Buganim Y, et al. Among authors: madar s. Cancer Res. 2010 Mar 15;70(6):2274-84. doi: 10.1158/0008-5472.CAN-09-2661. Epub 2010 Mar 2. Cancer Res. 2010. PMID: 20197462
43 results