Acher FC - Search Results

1

Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach.

Mony L, Triballeau N, Paoletti P, Acher FC, Bertrand HO. Mony L, et al. Among authors: acher fc. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5552-8. doi: 10.1016/j.bmcl.2010.07.043. Epub 2010 Jul 15. Bioorg Med Chem Lett. 2010. PMID: 20692832

2

Conformational analysis of glutamic acid analogues as probes of glutamate receptors using molecular modelling and NMR methods. Comparison with specific agonists.

Todeschi N, Gharbi-Benarous J, Acher F, Larue V, Pin JP, Bockaert J, Azerad R, Girault JP. Todeschi N, et al. Bioorg Med Chem. 1997 Feb;5(2):335-52. doi: 10.1016/s0968-0896(96)00252-0. Bioorg Med Chem. 1997. PMID: 9061198

3

Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes.

Acher FC, Tellier FJ, Azerad R, Brabet IN, Fagni L, Pin JP. Acher FC, et al. J Med Chem. 1997 Sep 12;40(19):3119-29. doi: 10.1021/jm970207b. J Med Chem. 1997. PMID: 9301676

4

Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.

Jullian N, Brabet I, Pin JP, Acher FC. Jullian N, et al. Among authors: acher fc. J Med Chem. 1999 May 6;42(9):1546-55. doi: 10.1021/jm980571q. J Med Chem. 1999. PMID: 10229625

5

Three-dimensional model of the extracellular domain of the type 4a metabotropic glutamate receptor: new insights into the activation process.

Bessis AS, Bertrand HO, Galvez T, De Colle C, Pin JP, Acher F. Bessis AS, et al. Protein Sci. 2000 Nov;9(11):2200-9. doi: 10.1110/ps.9.11.2200. Protein Sci. 2000. PMID: 11152130 Free PMC article.

6

New probes of the agonist binding site of metabotropic glutamate receptors.

Bessis AS, Bolte J, Pin JP, Acher F. Bessis AS, et al. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1569-72. doi: 10.1016/s0960-894x(01)00158-5. Bioorg Med Chem Lett. 2001. PMID: 11412983

7

Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity.

Bertrand HO, Bessis AS, Pin JP, Acher FC. Bertrand HO, et al. Among authors: acher fc. J Med Chem. 2002 Jul 18;45(15):3171-83. doi: 10.1021/jm010323l. J Med Chem. 2002. PMID: 12109902

8

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.

Bessis AS, Rondard P, Gaven F, Brabet I, Triballeau N, Prezeau L, Acher F, Pin JP. Bessis AS, et al. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11097-102. doi: 10.1073/pnas.162138699. Epub 2002 Jul 31. Proc Natl Acad Sci U S A. 2002. PMID: 12151600 Free PMC article.

9

Molecular determinants of ligand selectivity in a vertebrate odorant receptor.

Luu P, Acher F, Bertrand HO, Fan J, Ngai J. Luu P, et al. J Neurosci. 2004 Nov 10;24(45):10128-37. doi: 10.1523/JNEUROSCI.3117-04.2004. J Neurosci. 2004. PMID: 15537883 Free PMC article.

10

Odorant receptor specificities and receptor combinatorials: implications for olfactory coding.

Luu P, Acher F, Bertrand HO, Ngai J. Luu P, et al. Chem Senses. 2005 Jan;30 Suppl 1:i97-8. doi: 10.1093/chemse/bjh132. Chem Senses. 2005. PMID: 15738215 Review. No abstract available.

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