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Page 1
Effects of St. John's wort on irinotecan metabolism.
Mathijssen RH, Verweij J, de Bruijn P, Loos WJ, Sparreboom A. Mathijssen RH, et al. J Natl Cancer Inst. 2002 Aug 21;94(16):1247-9. doi: 10.1093/jnci/94.16.1247. J Natl Cancer Inst. 2002. PMID: 12189228 Free article. Clinical Trial.
Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor.
Sparreboom A, Kehrer DF, Mathijssen RH, Xie R, de Jonge MJ, de Bruijn P, Planting AS, Eskens FA, Verheij C, de Heus G, Klaren A, Zhang S, Verhaeghe T, Palmer PA, Verweij J. Sparreboom A, et al. Among authors: mathijssen rh. Br J Cancer. 2004 Apr 19;90(8):1508-15. doi: 10.1038/sj.bjc.6601732. Br J Cancer. 2004. PMID: 15083177 Free PMC article. Clinical Trial.
Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.
Lepper ER, Baker SD, Permenter M, Ries N, van Schaik RH, Schenk PW, Price DK, Ahn D, Smith NF, Cusatis G, Ingersoll RG, Bates SE, Mathijssen RH, Verweij J, Figg WD, Sparreboom A. Lepper ER, et al. Among authors: mathijssen rh. Clin Cancer Res. 2005 Oct 15;11(20):7398-404. doi: 10.1158/1078-0432.CCR-05-0520. Clin Cancer Res. 2005. PMID: 16243813 Clinical Trial.
A pharmacokinetic interaction study of docetaxel and cisplatin plus or minus 5-fluorouracil in the treatment of patients with recurrent or metastatic solid tumors.
Felici A, Loos WJ, Verweij J, Cirillo I, de Bruijn P, Nooter K, Mathijssen RH, de Jonge MJ. Felici A, et al. Among authors: mathijssen rh. Cancer Chemother Pharmacol. 2006 Nov;58(5):673-80. doi: 10.1007/s00280-006-0221-x. Epub 2006 Mar 17. Cancer Chemother Pharmacol. 2006. PMID: 16544143 Clinical Trial.
Prophylaxis of irinotecan-induced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study.
de Jong FA, Kehrer DF, Mathijssen RH, Creemers GJ, de Bruijn P, van Schaik RH, Planting AS, van der Gaast A, Eskens FA, Janssen JT, Ruit JB, Verweij J, Sparreboom A, de Jonge MJ. de Jong FA, et al. Among authors: mathijssen rh. Oncologist. 2006 Sep;11(8):944-54. doi: 10.1634/theoncologist.11-8-944. Oncologist. 2006. PMID: 16951398 Free article. Clinical Trial.
421 results