Asara J - Search Results

1

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase.

Inuzuka H, Tseng A, Gao D, Zhai B, Zhang Q, Shaik S, Wan L, Ang XL, Mock C, Yin H, Stommel JM, Gygi S, Lahav G, Asara J, Xiao ZX, Kaelin WG Jr, Harper JW, Wei W. Inuzuka H, et al. Among authors: asara j. Cancer Cell. 2010 Aug 9;18(2):147-59. doi: 10.1016/j.ccr.2010.06.015. Cancer Cell. 2010. PMID: 20708156 Free PMC article.

2

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.

Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG Jr. Ivan M, et al. Among authors: asara jm. Science. 2001 Apr 20;292(5516):464-8. doi: 10.1126/science.1059817. Epub 2001 Apr 5. Science. 2001. PMID: 11292862

3

Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation.

Zheng B, Jeong JH, Asara JM, Yuan YY, Granter SR, Chin L, Cantley LC. Zheng B, et al. Mol Cell. 2009 Jan 30;33(2):237-47. doi: 10.1016/j.molcel.2008.12.026. Mol Cell. 2009. PMID: 19187764 Free PMC article.

4

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.

Hutti JE, Shen RR, Abbott DW, Zhou AY, Sprott KM, Asara JM, Hahn WC, Cantley LC. Hutti JE, et al. Mol Cell. 2009 May 14;34(4):461-72. doi: 10.1016/j.molcel.2009.04.031. Mol Cell. 2009. PMID: 19481526 Free PMC article.

5

Regulation of oxysterol-binding protein Golgi localization through protein kinase D-mediated phosphorylation.

Nhek S, Ngo M, Yang X, Ng MM, Field SJ, Asara JM, Ridgway ND, Toker A. Nhek S, et al. Among authors: asara jm. Mol Biol Cell. 2010 Jul 1;21(13):2327-37. doi: 10.1091/mbc.e10-02-0090. Epub 2010 May 5. Mol Biol Cell. 2010. PMID: 20444975 Free PMC article.

6

Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer.

Yang X, Turke AB, Qi J, Song Y, Rexer BN, Miller TW, Jänne PA, Arteaga CL, Cantley LC, Engelman JA, Asara JM. Yang X, et al. Among authors: asara jm. Cancer Res. 2011 Sep 15;71(18):5965-75. doi: 10.1158/0008-5472.CAN-11-0445. Epub 2011 Jul 20. Cancer Res. 2011. PMID: 21775521 Free PMC article.

7

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.

Yi CH, Pan H, Seebacher J, Jang IH, Hyberts SG, Heffron GJ, Vander Heiden MG, Yang R, Li F, Locasale JW, Sharfi H, Zhai B, Rodriguez-Mias R, Luithardt H, Cantley LC, Daley GQ, Asara JM, Gygi SP, Wagner G, Liu CF, Yuan J. Yi CH, et al. Among authors: asara jm. Cell. 2011 Aug 19;146(4):607-20. doi: 10.1016/j.cell.2011.06.050. Cell. 2011. PMID: 21854985 Free PMC article.

8

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

Gao D, Inuzuka H, Tan MK, Fukushima H, Locasale JW, Liu P, Wan L, Zhai B, Chin YR, Shaik S, Lyssiotis CA, Gygi SP, Toker A, Cantley LC, Asara JM, Harper JW, Wei W. Gao D, et al. Among authors: asara jm. Mol Cell. 2011 Oct 21;44(2):290-303. doi: 10.1016/j.molcel.2011.08.030. Mol Cell. 2011. PMID: 22017875 Free PMC article.

9

SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.

Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W. Fukushima H, et al. Cell Rep. 2012 May 31;1(5):434-43. doi: 10.1016/j.celrep.2012.04.002. Cell Rep. 2012. PMID: 22708077 Free PMC article.

10

Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.

Liu Y, Marks K, Cowley GS, Carretero J, Liu Q, Nieland TJ, Xu C, Cohoon TJ, Gao P, Zhang Y, Chen Z, Altabef AB, Tchaicha JH, Wang X, Choe S, Driggers EM, Zhang J, Bailey ST, Sharpless NE, Hayes DN, Patel NM, Janne PA, Bardeesy N, Engelman JA, Manning BD, Shaw RJ, Asara JM, Scully R, Kimmelman A, Byers LA, Gibbons DL, Wistuba II, Heymach JV, Kwiatkowski DJ, Kim WY, Kung AL, Gray NS, Root DE, Cantley LC, Wong KK. Liu Y, et al. Among authors: asara jm. Cancer Discov. 2013 Aug;3(8):870-9. doi: 10.1158/2159-8290.CD-13-0015. Epub 2013 May 28. Cancer Discov. 2013. PMID: 23715154 Free PMC article.

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