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Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering.
Sandberg A, Luheshi LM, Söllvander S, Pereira de Barros T, Macao B, Knowles TP, Biverstål H, Lendel C, Ekholm-Petterson F, Dubnovitsky A, Lannfelt L, Dobson CM, Härd T. Sandberg A, et al. Among authors: dobson cm. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15595-600. doi: 10.1073/pnas.1001740107. Epub 2010 Aug 16. Proc Natl Acad Sci U S A. 2010. PMID: 20713699 Free PMC article.
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.
Cohen SI, Linse S, Luheshi LM, Hellstrand E, White DA, Rajah L, Otzen DE, Vendruscolo M, Dobson CM, Knowles TP. Cohen SI, et al. Among authors: dobson cm. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9758-63. doi: 10.1073/pnas.1218402110. Epub 2013 May 23. Proc Natl Acad Sci U S A. 2013. PMID: 23703910 Free PMC article.
Kinetic diversity of amyloid oligomers.
Dear AJ, Michaels TCT, Meisl G, Klenerman D, Wu S, Perrett S, Linse S, Dobson CM, Knowles TPJ. Dear AJ, et al. Among authors: dobson cm. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12087-12094. doi: 10.1073/pnas.1922267117. Epub 2020 May 15. Proc Natl Acad Sci U S A. 2020. PMID: 32414930 Free PMC article.
Characterization of the nanoscale properties of individual amyloid fibrils.
Smith JF, Knowles TP, Dobson CM, Macphee CE, Welland ME. Smith JF, et al. Among authors: dobson cm. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15806-11. doi: 10.1073/pnas.0604035103. Epub 2006 Oct 12. Proc Natl Acad Sci U S A. 2006. PMID: 17038504 Free PMC article.
Methods and models in neurodegenerative and systemic protein aggregation diseases.
Brorsson AC, Kumita JR, MacLeod I, Bolognesi B, Speretta E, Luheshi LM, Knowles TP, Dobson CM, Crowther DC. Brorsson AC, et al. Among authors: dobson cm. Front Biosci (Landmark Ed). 2010 Jan 1;15(1):373-96. doi: 10.2741/3626. Front Biosci (Landmark Ed). 2010. PMID: 20036826 Free article. Review.
804 results