Dedhar S - Search Results

1

Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.

auf dem Keller U, Bellac CL, Li Y, Lou Y, Lange PF, Ting R, Harwig C, Kappelhoff R, Dedhar S, Adam MJ, Ruth TJ, Bénard F, Perrin DM, Overall CM. auf dem Keller U, et al. Among authors: dedhar s. Cancer Res. 2010 Oct 1;70(19):7562-9. doi: 10.1158/0008-5472.CAN-10-1584. Epub 2010 Aug 20. Cancer Res. 2010. PMID: 20729277

2

Specific alterations in the expression of alpha 3 beta 1 and alpha 6 beta 4 integrins in highly invasive and metastatic variants of human prostate carcinoma cells selected by in vitro invasion through reconstituted basement membrane.

Dedhar S, Saulnier R, Nagle R, Overall CM. Dedhar S, et al. Clin Exp Metastasis. 1993 Sep;11(5):391-400. doi: 10.1007/BF00132982. Clin Exp Metastasis. 1993. PMID: 8375114

3

Inhibition of tumor cell invasion and angiogenesis by motuporamines.

Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, Karsan A, Andersen RJ, Dedhar S, Roberge M. Roskelley CD, et al. Among authors: dedhar s. Cancer Res. 2001 Sep 15;61(18):6788-94. Cancer Res. 2001. PMID: 11559552

4

The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange.

McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, Williams DE, Andersen RJ, Dedhar S, Roberge M, Roskelley CD. McHardy LM, et al. Among authors: dedhar s. Cancer Res. 2004 Feb 15;64(4):1468-74. doi: 10.1158/0008-5472.can-03-2733. Cancer Res. 2004. PMID: 14973060

5

Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.

Troussard AA, McDonald PC, Wederell ED, Mawji NM, Filipenko NR, Gelmon KA, Kucab JE, Dunn SE, Emerman JT, Bally MB, Dedhar S. Troussard AA, et al. Among authors: dedhar s. Cancer Res. 2006 Jan 1;66(1):393-403. doi: 10.1158/0008-5472.CAN-05-2304. Cancer Res. 2006. PMID: 16397254 Free article.

6

Inhibition of the phosphatidylinositol 3'-kinase pathway promotes autocrine Fas-induced death of phosphatase and tensin homologue-deficient prostate cancer cells.

Bertram J, Peacock JW, Tan C, Mui AL, Chung SW, Gleave ME, Dedhar S, Cox ME, Ong CJ. Bertram J, et al. Among authors: dedhar s. Cancer Res. 2006 May 1;66(9):4781-8. doi: 10.1158/0008-5472.CAN-05-3173. Cancer Res. 2006. PMID: 16651432

7

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S. McDonald PC, et al. Among authors: dedhar s. Cancer Res. 2008 Mar 15;68(6):1618-24. doi: 10.1158/0008-5472.CAN-07-5869. Cancer Res. 2008. PMID: 18339839

8

Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis.

Lou Y, Preobrazhenska O, auf dem Keller U, Sutcliffe M, Barclay L, McDonald PC, Roskelley C, Overall CM, Dedhar S. Lou Y, et al. Among authors: dedhar s. Dev Dyn. 2008 Oct;237(10):2755-68. doi: 10.1002/dvdy.21658. Dev Dyn. 2008. PMID: 18773493 Free article.

9

QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model.

Kalra J, Warburton C, Fang K, Edwards L, Daynard T, Waterhouse D, Dragowska W, Sutherland BW, Dedhar S, Gelmon K, Bally M. Kalra J, et al. Among authors: dedhar s. Breast Cancer Res. 2009;11(3):R25. doi: 10.1186/bcr2252. Epub 2009 May 1. Breast Cancer Res. 2009. PMID: 19409087 Free PMC article.

10

The importance of integrin-linked kinase in the regulation of bladder cancer invasion.

Matsui Y, Assi K, Ogawa O, Raven PA, Dedhar S, Gleave ME, Salh B, So AI. Matsui Y, et al. Among authors: dedhar s. Int J Cancer. 2012 Feb 1;130(3):521-31. doi: 10.1002/ijc.26008. Epub 2011 May 28. Int J Cancer. 2012. PMID: 21351095

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