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The promyelocytic leukemia zinc finger (PLZF) protein exerts neuroprotective effects in neuronal cells and is dysregulated in experimental stroke.
Seidel K, Kirsch S, Lucht K, Zaade D, Reinemund J, Schmitz J, Klare S, Li Y, Schefe JH, Schmerbach K, Goldin-Lang P, Zollmann FS, Thöne-Reineke C, Unger T, Funke-Kaiser H. Seidel K, et al. Among authors: schmitz j. Brain Pathol. 2011 Jan;21(1):31-43. doi: 10.1111/j.1750-3639.2010.00427.x. Brain Pathol. 2011. PMID: 20731660 Free PMC article.
The (pro)renin receptor mediates constitutive PLZF-independent pro-proliferative effects which are inhibited by bafilomycin but not genistein.
Kirsch S, Schrezenmeier E, Klare S, Zaade D, Seidel K, Schmitz J, Bernhard S, Lauer D, Slack M, Goldin-Lang P, Unger T, Zollmann FS, Funke-Kaiser H. Kirsch S, et al. Among authors: schmitz j. Int J Mol Med. 2014 Apr;33(4):795-808. doi: 10.3892/ijmm.2014.1624. Epub 2014 Jan 14. Int J Mol Med. 2014. PMID: 24424509 Free PMC article.
The (pro)renin receptor ((P)RR) can act as a repressor of Wnt signalling.
Bernhard SM, Seidel K, Schmitz J, Klare S, Kirsch S, Schrezenmeier E, Zaade D, Meyborg H, Goldin-Lang P, Stawowy P, Zollmann FS, Unger T, Funke-Kaiser H. Bernhard SM, et al. Among authors: schmitz j. Biochem Pharmacol. 2012 Dec 15;84(12):1643-50. doi: 10.1016/j.bcp.2012.09.020. Epub 2012 Sep 26. Biochem Pharmacol. 2012. PMID: 23022225
A polymorphic microsatellite repeat within the ECE-1c promoter is involved in transcriptional start site determination, human evolution, and Alzheimer's disease.
Li Y, Seidel K, Marschall P, Klein M, Hope A, Schacherl J, Schmitz J, Menk M, Schefe JH, Reinemund J, Hugel R, Walden P, Schlosser A, Volkmer R, Schimkus J, Kölsch H, Maier W, Kornhuber J, Frölich L, Klare S, Kirsch S, Schmerbach K, Scheele S, Grittner U, Zollmann F, Goldin-Lang P, Peters O, Kintscher U, Unger T, Funke-Kaiser H. Li Y, et al. Among authors: schmitz j. J Neurosci. 2012 Nov 21;32(47):16807-20. doi: 10.1523/JNEUROSCI.2636-12.2012. J Neurosci. 2012. PMID: 23175834 Free PMC article.
Heterozygous variants in the teashirt zinc finger homeobox 3 (TSHZ3) gene in human congenital anomalies of the kidney and urinary tract.
Kesdiren E, Martens H, Brand F, Werfel L, Wedekind L, Trowe MO, Schmitz J, Hennies I, Geffers R, Gucev Z, Seeman T, Schmidt S, Tasic V, Fasano L, Bräsen JH, Kispert A, Christians A, Haffner D, Weber RG. Kesdiren E, et al. Among authors: schmitz j. Eur J Hum Genet. 2024 Oct 17. doi: 10.1038/s41431-024-01710-y. Online ahead of print. Eur J Hum Genet. 2024. PMID: 39420202
1,654 results