Parsons N - Search Results

1

A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis.

Chataway J, Nicholas R, Todd S, Miller DH, Parsons N, Valdés-Márquez E, Stallard N, Friede T. Chataway J, et al. Among authors: parsons n. Mult Scler. 2011 Jan;17(1):81-8. doi: 10.1177/1352458510382129. Epub 2010 Aug 26. Mult Scler. 2011. PMID: 20798135

2

Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis.

Friede T, Parsons N, Stallard N, Todd S, Valdes Marquez E, Chataway J, Nicholas R. Friede T, et al. Among authors: parsons n. Stat Med. 2011 Jun 15;30(13):1528-40. doi: 10.1002/sim.4202. Epub 2011 Feb 22. Stat Med. 2011. PMID: 21341301

3

A conditional error function approach for subgroup selection in adaptive clinical trials.

Friede T, Parsons N, Stallard N. Friede T, et al. Among authors: parsons n. Stat Med. 2012 Dec 30;31(30):4309-20. doi: 10.1002/sim.5541. Epub 2012 Aug 3. Stat Med. 2012. PMID: 22865774

4

Adaptive designs for confirmatory clinical trials with subgroup selection.

Stallard N, Hamborg T, Parsons N, Friede T. Stallard N, et al. Among authors: parsons n. J Biopharm Stat. 2014;24(1):168-87. doi: 10.1080/10543406.2013.857238. J Biopharm Stat. 2014. PMID: 24392984 Review.

5

A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints.

Kunz CU, Friede T, Parsons N, Todd S, Stallard N. Kunz CU, et al. Among authors: parsons n. J Biopharm Stat. 2015;25(1):170-89. doi: 10.1080/10543406.2013.840646. J Biopharm Stat. 2015. PMID: 24697322 Free PMC article.

6

Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data.

Kunz CU, Friede T, Parsons N, Todd S, Stallard N. Kunz CU, et al. Among authors: parsons n. Pharm Stat. 2014 Jul-Aug;13(4):238-46. doi: 10.1002/pst.1619. Epub 2014 May 2. Pharm Stat. 2014. PMID: 24789367 Free PMC article.

7

Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial.

Stallard N, Kunz CU, Todd S, Parsons N, Friede T. Stallard N, et al. Among authors: parsons n. Stat Med. 2015 Oct 15;34(23):3104-15. doi: 10.1002/sim.6567. Epub 2015 Jun 26. Stat Med. 2015. PMID: 26112909 Free PMC article.

8

Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations.

Kunz CU, Stallard N, Parsons N, Todd S, Friede T. Kunz CU, et al. Among authors: parsons n. Biom J. 2017 Mar;59(2):344-357. doi: 10.1002/bimj.201500233. Epub 2016 Nov 25. Biom J. 2017. PMID: 27886393 Free PMC article.

9

Decision-theoretic designs for a series of trials with correlated treatment effects using the Sarmanov multivariate beta-binomial distribution.

Hee SW, Parsons N, Stallard N. Hee SW, et al. Among authors: parsons n. Biom J. 2018 Mar;60(2):232-245. doi: 10.1002/bimj.201600202. Epub 2017 Jul 26. Biom J. 2018. PMID: 28744892 Free PMC article.

10

An adaptive two-arm clinical trial using early endpoints to inform decision making: design for a study of sub-acromial spacers for repair of rotator cuff tendon tears.

Parsons N, Stallard N, Parsons H, Wells P, Underwood M, Mason J, Metcalfe A. Parsons N, et al. Among authors: parsons h. Trials. 2019 Dec 9;20(1):694. doi: 10.1186/s13063-019-3708-6. Trials. 2019. PMID: 31815651 Free PMC article.

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