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Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult.
Motoda L, Osato M, Yamashita N, Jacob B, Chen LQ, Yanagida M, Ida H, Wee HJ, Sun AX, Taniuchi I, Littman D, Ito Y. Motoda L, et al. Among authors: yamashita n. Stem Cells. 2007 Dec;25(12):2976-86. doi: 10.1634/stemcells.2007-0061. Epub 2007 Sep 6. Stem Cells. 2007. PMID: 17823240
Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation.
Morrison NA, Stephens AA, Osato M, Polly P, Tan TC, Yamashita N, Doecke JD, Pasco J, Fozzard N, Jones G, Ralston SH, Sambrook PN, Prince RL, Nicholson GC. Morrison NA, et al. Among authors: yamashita n. PLoS One. 2012;7(8):e42617. doi: 10.1371/journal.pone.0042617. Epub 2012 Aug 13. PLoS One. 2012. PMID: 22912713 Free PMC article.
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects.
Wang CQ, Krishnan V, Tay LS, Chin DW, Koh CP, Chooi JY, Nah GS, Du L, Jacob B, Yamashita N, Lai SK, Tan TZ, Mori S, Tanuichi I, Tergaonkar V, Ito Y, Osato M. Wang CQ, et al. Among authors: yamashita n. Cell Rep. 2014 Aug 7;8(3):767-82. doi: 10.1016/j.celrep.2014.06.046. Epub 2014 Jul 24. Cell Rep. 2014. PMID: 25066130 Free article.
Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia.
Ong KOK, Mok MMH, Niibori-Nambu A, Du L, Yanagida M, Wang CQ, Bahirvani AG, Chin DWL, Koh CP, Ng KP, Yamashita N, Jacob B, Yokomizo T, Takizawa H, Matsumura T, Suda T, Lau JA, Tan TZ, Mori S, Yang H, Iwasaki M, Minami T, Asou N, Sun QY, Ding LW, Koeffler HP, Tenen DG, Shimizu R, Yamamoto M, Ito Y, Kham SKY, Yeoh AE, Chng WJ, Osato M. Ong KOK, et al. Among authors: yamashita n. Exp Hematol. 2024 Sep;137:104255. doi: 10.1016/j.exphem.2024.104255. Epub 2024 Jun 13. Exp Hematol. 2024. PMID: 38876252
1,385 results