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Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.
Peterson AJ, Menheniott TR, O'Connor L, Walduck AK, Fox JG, Kawakami K, Minamoto T, Ong EK, Wang TC, Judd LM, Giraud AS. Peterson AJ, et al. Among authors: judd lm. Gastroenterology. 2010 Dec;139(6):2005-17. doi: 10.1053/j.gastro.2010.08.043. Epub 2010 Aug 27. Gastroenterology. 2010. PMID: 20801119 Free PMC article.
The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development.
Howlett M, Giraud AS, Lescesen H, Jackson CB, Kalantzis A, Van Driel IR, Robb L, Van der Hoek M, Ernst M, Minamoto T, Boussioutas A, Oshima H, Oshima M, Judd LM. Howlett M, et al. Among authors: judd lm. Gastroenterology. 2009 Mar;136(3):967-77. doi: 10.1053/j.gastro.2008.12.003. Epub 2008 Dec 3. Gastroenterology. 2009. PMID: 19121317
Targeting STAT3 in gastric cancer.
Giraud AS, Menheniott TR, Judd LM. Giraud AS, et al. Among authors: judd lm. Expert Opin Ther Targets. 2012 Sep;16(9):889-901. doi: 10.1517/14728222.2012.709238. Epub 2012 Jul 26. Expert Opin Ther Targets. 2012. PMID: 22834702 Review.
Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations.
Buzzelli JN, O'Connor L, Scurr M, Chung Nien Chin S, Catubig A, Ng GZ, Oshima M, Oshima H, Giraud AS, Sutton P, Judd LM, Menheniott TR. Buzzelli JN, et al. Among authors: judd lm. Am J Physiol Gastrointest Liver Physiol. 2019 Feb 1;316(2):G251-G262. doi: 10.1152/ajpgi.00304.2018. Epub 2018 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30520693 Free article.
Cytokine signalling via gp130 in gastric cancer.
Howlett M, Menheniott TR, Judd LM, Giraud AS. Howlett M, et al. Among authors: judd lm. Biochim Biophys Acta. 2009 Nov;1793(11):1623-33. doi: 10.1016/j.bbamcr.2009.07.009. Epub 2009 Aug 7. Biochim Biophys Acta. 2009. PMID: 19665497 Free article. Review.
116 results