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Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.
Peterson AJ, Menheniott TR, O'Connor L, Walduck AK, Fox JG, Kawakami K, Minamoto T, Ong EK, Wang TC, Judd LM, Giraud AS. Peterson AJ, et al. Among authors: kawakami k. Gastroenterology. 2010 Dec;139(6):2005-17. doi: 10.1053/j.gastro.2010.08.043. Epub 2010 Aug 27. Gastroenterology. 2010. PMID: 20801119 Free PMC article.
Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing.
Tomita H, Takaishi S, Menheniott TR, Yang X, Shibata W, Jin G, Betz KS, Kawakami K, Minamoto T, Tomasetto C, Rio MC, Lerkowit N, Varro A, Giraud AS, Wang TC. Tomita H, et al. Among authors: kawakami k. Gastroenterology. 2011 Mar;140(3):879-91. doi: 10.1053/j.gastro.2010.11.037. Epub 2010 Nov 25. Gastroenterology. 2011. PMID: 21111741 Free PMC article.
[DNA methylation and cancer metastasis].
Kawakami K, Minamoto T. Kawakami K, et al. Gan To Kagaku Ryoho. 2010 Nov;37(11):2042-6. Gan To Kagaku Ryoho. 2010. PMID: 21084800 Review. Japanese.
Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine.
Shimasaki T, Ishigaki Y, Nakamura Y, Takata T, Nakaya N, Nakajima H, Sato I, Zhao X, Kitano A, Kawakami K, Tanaka T, Takegami T, Tomosugi N, Minamoto T, Motoo Y. Shimasaki T, et al. Among authors: kawakami k. J Gastroenterol. 2012 Mar;47(3):321-33. doi: 10.1007/s00535-011-0484-9. Epub 2011 Nov 1. J Gastroenterol. 2012. PMID: 22041920
Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling.
Pyko IV, Nakada M, Sabit H, Teng L, Furuyama N, Hayashi Y, Kawakami K, Minamoto T, Fedulau AS, Hamada J. Pyko IV, et al. Among authors: kawakami k. Carcinogenesis. 2013 Oct;34(10):2206-17. doi: 10.1093/carcin/bgt182. Epub 2013 May 28. Carcinogenesis. 2013. PMID: 23715499 Free article.
2,690 results