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Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.
Peterson AJ, Menheniott TR, O'Connor L, Walduck AK, Fox JG, Kawakami K, Minamoto T, Ong EK, Wang TC, Judd LM, Giraud AS. Peterson AJ, et al. Among authors: menheniott tr. Gastroenterology. 2010 Dec;139(6):2005-17. doi: 10.1053/j.gastro.2010.08.043. Epub 2010 Aug 27. Gastroenterology. 2010. PMID: 20801119 Free PMC article.
Overexpression of IL-11 promotes premalignant gastric epithelial hyperplasia in isolation from germline gp130-JAK-STAT driver mutations.
Buzzelli JN, O'Connor L, Scurr M, Chung Nien Chin S, Catubig A, Ng GZ, Oshima M, Oshima H, Giraud AS, Sutton P, Judd LM, Menheniott TR. Buzzelli JN, et al. Among authors: menheniott tr. Am J Physiol Gastrointest Liver Physiol. 2019 Feb 1;316(2):G251-G262. doi: 10.1152/ajpgi.00304.2018. Epub 2018 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30520693 Free article.
Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing.
Tomita H, Takaishi S, Menheniott TR, Yang X, Shibata W, Jin G, Betz KS, Kawakami K, Minamoto T, Tomasetto C, Rio MC, Lerkowit N, Varro A, Giraud AS, Wang TC. Tomita H, et al. Among authors: menheniott tr. Gastroenterology. 2011 Mar;140(3):879-91. doi: 10.1053/j.gastro.2010.11.037. Epub 2010 Nov 25. Gastroenterology. 2011. PMID: 21111741 Free PMC article.
Targeting STAT3 in gastric cancer.
Giraud AS, Menheniott TR, Judd LM. Giraud AS, et al. Among authors: menheniott tr. Expert Opin Ther Targets. 2012 Sep;16(9):889-901. doi: 10.1517/14728222.2012.709238. Epub 2012 Jul 26. Expert Opin Ther Targets. 2012. PMID: 22834702 Review.
RUNX3 methylation and anti-tumor immunity.
Menheniott TR, Judd LM, Giraud AS. Menheniott TR, et al. Oncoscience. 2015 Sep 12;2(10):789-90. doi: 10.18632/oncoscience.242. eCollection 2015. Oncoscience. 2015. PMID: 26682246 Free PMC article. No abstract available.
44 results