Coughlin CM - Search Results

1

Approaches and limitations of phosphatidylinositol-3-kinase pathway activation status as a predictive biomarker in the clinical development of targeted therapy.

Coughlin CM, Johnston DS, Strahs A, Burczynski ME, Bacus S, Hill J, Feingold JM, Zacharchuk C, Berkenblit A. Coughlin CM, et al. Breast Cancer Res Treat. 2010 Nov;124(1):1-11. doi: 10.1007/s10549-010-1108-4. Epub 2010 Aug 28. Breast Cancer Res Treat. 2010. PMID: 20803067 Review.

2

Opportunities posed by novel patient selection biomarker approaches in oncology drug development: going beyond the cytotoxics.

Sellar G, Alvarez JD, Loganzo F, Abbas R, Immermann F, Karnoub M, Feuerstein GZ, Burczynski ME, Coughlin CM. Sellar G, et al. Among authors: coughlin cm. Biomark Med. 2008 Apr;2(2):147-53. doi: 10.2217/17520363.2.2.147. Biomark Med. 2008. PMID: 20477436

3

Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors in vivo.

Reid GS, Shan X, Coughlin CM, Lassoued W, Pawel BR, Wexler LH, Thiele CJ, Tsokos M, Pinkus JL, Pinkus GS, Grupp SA, Vonderheide RH. Reid GS, et al. Among authors: coughlin cm. Clin Cancer Res. 2009 Nov 1;15(21):6602-8. doi: 10.1158/1078-0432.CCR-09-0829. Epub 2009 Oct 13. Clin Cancer Res. 2009. PMID: 19825945 Free PMC article. Clinical Trial.

4

Interferon beta adenoviral gene therapy in a patient with ovarian cancer.

Sterman DH, Gillespie CT, Carroll RG, Coughlin CM, Lord EM, Sun J, Haas A, Recio A, Kaiser LR, Coukos G, June CH, Albelda SM, Vonderheide RH. Sterman DH, et al. Among authors: coughlin cm. Nat Clin Pract Oncol. 2006 Nov;3(11):633-9. doi: 10.1038/ncponc0658. Nat Clin Pract Oncol. 2006. PMID: 17080181

5

B7-1 and interleukin 12 synergistically induce effective antitumor immunity.

Coughlin CM, Wysocka M, Kurzawa HL, Lee WM, Trinchieri G, Eck SL. Coughlin CM, et al. Cancer Res. 1995 Nov 1;55(21):4980-7. Cancer Res. 1995. PMID: 7585539

6

The effect of interleukin 12 desensitization on the antitumor efficacy of recombinant interleukin 12.

Coughlin CM, Wysocka M, Trinchieri G, Lee WM. Coughlin CM, et al. Cancer Res. 1997 Jun 15;57(12):2460-7. Cancer Res. 1997. PMID: 9192826

7

Phosphatidylinositol 3-Kinase α-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.

Juric D, Rodon J, Tabernero J, Janku F, Burris HA, Schellens JHM, Middleton MR, Berlin J, Schuler M, Gil-Martin M, Rugo HS, Seggewiss-Bernhardt R, Huang A, Bootle D, Demanse D, Blumenstein L, Coughlin C, Quadt C, Baselga J. Juric D, et al. J Clin Oncol. 2018 May 1;36(13):1291-1299. doi: 10.1200/JCO.2017.72.7107. Epub 2018 Feb 5. J Clin Oncol. 2018. PMID: 29401002 Free PMC article. Clinical Trial.

8

Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis.

Coughlin CM, Salhany KE, Wysocka M, Aruga E, Kurzawa H, Chang AE, Hunter CA, Fox JC, Trinchieri G, Lee WM. Coughlin CM, et al. J Clin Invest. 1998 Mar 15;101(6):1441-52. doi: 10.1172/JCI1555. J Clin Invest. 1998. PMID: 9502787 Free PMC article.

9

Targeting adult and pediatric cancers via cell-based vaccines and the prospect of activated B lymphocytes as a novel modality.

Coughlin CM, Vonderheide RH. Coughlin CM, et al. Cancer Biol Ther. 2003 Sep-Oct;2(5):466-70. doi: 10.4161/cbt.2.5.445. Cancer Biol Ther. 2003. PMID: 14614310 Free article. Review.

10

Immunosurveillance and survivin-specific T-cell immunity in children with high-risk neuroblastoma.

Coughlin CM, Fleming MD, Carroll RG, Pawel BR, Hogarty MD, Shan X, Vance BA, Cohen JN, Jairaj S, Lord EM, Wexler MH, Danet-Desnoyers GA, Pinkus JL, Pinkus GS, Maris JM, Grupp SA, Vonderheide RH. Coughlin CM, et al. J Clin Oncol. 2006 Dec 20;24(36):5725-34. doi: 10.1200/JCO.2005.05.3314. J Clin Oncol. 2006. PMID: 17179106

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