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Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection.
Brockman MA, Brumme ZL, Brumme CJ, Miura T, Sela J, Rosato PC, Kadie CM, Carlson JM, Markle TJ, Streeck H, Kelleher AD, Markowitz M, Jessen H, Rosenberg E, Altfeld M, Harrigan PR, Heckerman D, Walker BD, Allen TM. Brockman MA, et al. Among authors: kelleher ad. J Virol. 2010 Nov;84(22):11937-49. doi: 10.1128/JVI.01086-10. Epub 2010 Sep 1. J Virol. 2010. PMID: 20810731 Free PMC article.
Comprehensive analyses of a unique HIV-1-infected nonprogressor reveal a complex association of immunobiological mechanisms in the context of replication-incompetent infection.
Wang B, Dyer WB, Zaunders JJ, Mikhail M, Sullivan JS, Williams L, Haddad DN, Harris G, Holt JA, Cooper DA, Miranda-Saksena M, Boadle R, Kelleher AD, Saksena NK. Wang B, et al. Among authors: kelleher ad. Virology. 2002 Dec 20;304(2):246-64. doi: 10.1006/viro.2002.1706. Virology. 2002. PMID: 12504566 Free article.
Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection.
Zaunders JJ, Ip S, Munier ML, Kaufmann DE, Suzuki K, Brereton C, Sasson SC, Seddiki N, Koelsch K, Landay A, Grey P, Finlayson R, Kaldor J, Rosenberg ES, Walker BD, Fazekas de St Groth B, Cooper DA, Kelleher AD. Zaunders JJ, et al. Among authors: kelleher ad. J Virol. 2006 Oct;80(20):10162-72. doi: 10.1128/JVI.00249-06. J Virol. 2006. PMID: 17005693 Free PMC article.
Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles.
Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. Streeck H, et al. J Virol. 2007 Jul;81(14):7725-31. doi: 10.1128/JVI.00708-07. Epub 2007 May 9. J Virol. 2007. PMID: 17494064 Free PMC article.
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.
Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, Le Gall S, Rinaldo CR, Craggs SL, Allgaier RL, Power KA, Kuntzen T, Tung CS, LaBute MX, Mueller SM, Harrer T, McMichael AJ, Goulder PJ, Aiken C, Brander C, Kelleher AD, Allen TM. Schneidewind A, et al. Among authors: kelleher ad. J Virol. 2007 Nov;81(22):12382-93. doi: 10.1128/JVI.01543-07. Epub 2007 Sep 5. J Virol. 2007. PMID: 17804494 Free PMC article.
292 results