Pagès L - Search Results

1

Synthesis and biological activity of pyrido[3',2':4,5]thieno[3,2-d]pyrimidines as phosphodiesterase type 4 inhibitors.

Taltavull J, Serrat J, Gràcia J, Gavaldà A, Andrés M, Córdoba M, Miralpeix M, Vilella D, Beleta J, Ryder H, Pagès L. Taltavull J, et al. Among authors: pages l. J Med Chem. 2010 Oct 14;53(19):6912-22. doi: 10.1021/jm100524j. J Med Chem. 2010. PMID: 20825218

2

Synthesis and structure-activity relationships of novel histamine H1 antagonists: indolylpiperidinyl benzoic acid derivatives.

Fonquerna S, Miralpeix M, Pagès L, Puig C, Cardús A, Antón F, Cárdenas A, Vilella D, Aparici M, Calaf E, Prieto J, Gras J, Huerta JM, Warrellow G, Beleta J, Ryder H. Fonquerna S, et al. Among authors: pages l. J Med Chem. 2004 Dec 2;47(25):6326-37. doi: 10.1021/jm0498203. J Med Chem. 2004. PMID: 15566302

3

Synthesis and structure-activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H1 antagonists.

Fonquerna S, Miralpeix M, Pagès L, Puig C, Cardús A, Antón F, Vilella D, Aparici M, Prieto J, Warrellow G, Beleta J, Ryder H. Fonquerna S, et al. Among authors: pages l. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1165-7. doi: 10.1016/j.bmcl.2004.12.008. Bioorg Med Chem Lett. 2005. PMID: 15686934

4

Synthesis and biological activity of pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as novel and potent phosphodiesterase type 4 inhibitors.

Taltavull J, Serrat J, Gràcia J, Gavaldà A, Córdoba M, Calama E, Montero JL, Andrés M, Miralpeix M, Vilella D, Hernández B, Beleta J, Ryder H, Pagès L. Taltavull J, et al. Among authors: pages l. Eur J Med Chem. 2011 Oct;46(10):4946-56. doi: 10.1016/j.ejmech.2011.07.054. Epub 2011 Aug 5. Eur J Med Chem. 2011. PMID: 21871695

5

Biphenyl Pyridazinone Derivatives as Inhaled PDE4 Inhibitors: Structural Biology and Structure-Activity Relationships.

Gràcia J, Buil MA, Castro J, Eichhorn P, Ferrer M, Gavaldà A, Hernández B, Segarra V, Lehner MD, Moreno I, Pagès L, Roberts RS, Serrat J, Sevilla S, Taltavull J, Andrés M, Cabedo J, Vilella D, Calama E, Carcasona C, Miralpeix M. Gràcia J, et al. Among authors: pages l. J Med Chem. 2016 Dec 8;59(23):10479-10497. doi: 10.1021/acs.jmedchem.6b00829. Epub 2016 Nov 17. J Med Chem. 2016. PMID: 27933955

6

Design, synthesis, and biological activities of new thieno[3,2-d] pyrimidines as selective type 4 phosphodiesterase inhibitors.

Crespo MI, Pagès L, Vega A, Segarra V, López M, Doménech T, Miralpeix M, Beleta J, Ryder H, Palacios JM. Crespo MI, et al. Among authors: pages l. J Med Chem. 1998 Oct 8;41(21):4021-35. doi: 10.1021/jm981012m. J Med Chem. 1998. PMID: 9767640

7

Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.

Bonjoch J, Diaba F, Pagès L, Pérez D, Soca L, Miralpeix M, Vilella D, Anton P, Puig C. Bonjoch J, et al. Among authors: pages l. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4299-302. doi: 10.1016/j.bmcl.2009.05.094. Epub 2009 May 27. Bioorg Med Chem Lett. 2009. PMID: 19505824

8

PDE4 inhibitors: a review of current developments (2005 - 2009).

Pagès L, Gavaldà A, Lehner MD. Pagès L, et al. Expert Opin Ther Pat. 2009 Nov;19(11):1501-19. doi: 10.1517/13543770903313753. Expert Opin Ther Pat. 2009. PMID: 19832118 Review.

9

Discovery of a Novel Inhaled PI3Kδ Inhibitor for the Treatment of Respiratory Diseases.

Erra M, Taltavull J, Bernal FJ, Caturla JF, Carrascal M, Pagès L, Mir M, Espinosa S, Gràcia J, Domínguez M, Sabaté M, Paris S, Maldonado M, Hernández B, Bravo M, Calama E, Miralpeix M, Lehner MD, Calbet M. Erra M, et al. Among authors: pages l. J Med Chem. 2018 Nov 8;61(21):9551-9567. doi: 10.1021/acs.jmedchem.8b00873. Epub 2018 Oct 29. J Med Chem. 2018. PMID: 30351000

10

α2,3-Sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.

Pérez-Garay M, Arteta B, Llop E, Cobler L, Pagès L, Ortiz R, Ferri MJ, de Bolós C, Figueras J, de Llorens R, Vidal-Vanaclocha F, Peracaula R. Pérez-Garay M, et al. Among authors: pages l. Int J Biochem Cell Biol. 2013 Aug;45(8):1748-57. doi: 10.1016/j.biocel.2013.05.015. Epub 2013 May 29. Int J Biochem Cell Biol. 2013. PMID: 23726834

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