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A novel peptide agonist of formyl-peptide receptor-like 1 (ALX) displays anti-inflammatory and cardioprotective effects.
Hecht I, Rong J, Sampaio AL, Hermesh C, Rutledge C, Shemesh R, Toporik A, Beiman M, Dassa L, Niv H, Cojocaru G, Zauberman A, Rotman G, Perretti M, Vinten-Johansen J, Cohen Y. Hecht I, et al. Among authors: rotman g. J Pharmacol Exp Ther. 2009 Feb;328(2):426-34. doi: 10.1124/jpet.108.145821. Epub 2008 Nov 20. J Pharmacol Exp Ther. 2009. PMID: 19023040
Discovery and validation of novel peptide agonists for G-protein-coupled receptors.
Shemesh R, Toporik A, Levine Z, Hecht I, Rotman G, Wool A, Dahary D, Gofer E, Kliger Y, Soffer MA, Rosenberg A, Eshel D, Cohen Y. Shemesh R, et al. Among authors: rotman g. J Biol Chem. 2008 Dec 12;283(50):34643-9. doi: 10.1074/jbc.M805181200. Epub 2008 Oct 9. J Biol Chem. 2008. PMID: 18854305 Free PMC article.
A novel recombinant soluble splice variant of Met is a potent antagonist of the hepatocyte growth factor/scatter factor-Met pathway.
Tiran Z, Oren A, Hermesh C, Rotman G, Levine Z, Amitai H, Handelsman T, Beiman M, Chen A, Landesman-Milo D, Dassa L, Peres Y, Koifman C, Glezer S, Vidal-Finkelstein R, Bahat K, Pergam T, Israel C, Horev J, Tsarfaty I, Ayalon-Soffer M. Tiran Z, et al. Among authors: rotman g. Clin Cancer Res. 2008 Jul 15;14(14):4612-21. doi: 10.1158/1078-0432.CCR-08-0108. Clin Cancer Res. 2008. PMID: 18628476
A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization.
Palmer GM, Tiran Z, Zhou Z, Capozzi ME, Park W, Coletta C, Pyriochou A, Kliger Y, Levy O, Borukhov I, Dewhirst MW, Rotman G, Penn JS, Papapetropoulos A. Palmer GM, et al. Among authors: rotman g. Br J Pharmacol. 2012 Mar;165(6):1891-1903. doi: 10.1111/j.1476-5381.2011.01677.x. Br J Pharmacol. 2012. PMID: 21943108 Free PMC article.
ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses.
Hecht I, Toporik A, Podojil JR, Vaknin I, Cojocaru G, Oren A, Aizman E, Liang SC, Leung L, Dicken Y, Novik A, Marbach-Bar N, Elmesmari A, Tange C, Gilmour A, McIntyre D, Kurowska-Stolarska M, McNamee K, Leitner J, Greenwald S, Dassa L, Levine Z, Steinberger P, Williams RO, Miller SD, McInnes IB, Neria E, Rotman G. Hecht I, et al. Among authors: rotman g. J Immunol. 2018 Mar 15;200(6):2025-2037. doi: 10.4049/jimmunol.1700325. Epub 2018 Feb 5. J Immunol. 2018. PMID: 29431694 Free PMC article.
Unusual alternative splicing within the human kallikrein genes KLK2 and KLK3 gives rise to novel prostate-specific proteins.
David A, Mabjeesh N, Azar I, Biton S, Engel S, Bernstein J, Romano J, Avidor Y, Waks T, Eshhar Z, Langer SZ, Lifschitz-Mercer B, Matzkin H, Rotman G, Toporik A, Savitsky K, Mintz L. David A, et al. Among authors: rotman g. J Biol Chem. 2002 May 17;277(20):18084-90. doi: 10.1074/jbc.M102285200. Epub 2002 Feb 7. J Biol Chem. 2002. PMID: 11834722 Free article.
Widespread occurrence of antisense transcription in the human genome.
Yelin R, Dahary D, Sorek R, Levanon EY, Goldstein O, Shoshan A, Diber A, Biton S, Tamir Y, Khosravi R, Nemzer S, Pinner E, Walach S, Bernstein J, Savitsky K, Rotman G. Yelin R, et al. Among authors: rotman g. Nat Biotechnol. 2003 Apr;21(4):379-86. doi: 10.1038/nbt808. Epub 2003 Mar 17. Nat Biotechnol. 2003. PMID: 12640466
62 results