Iskar M - Search Results

1

Drug-induced regulation of target expression.

Iskar M, Campillos M, Kuhn M, Jensen LJ, van Noort V, Bork P. Iskar M, et al. PLoS Comput Biol. 2010 Sep 9;6(9):e1000925. doi: 10.1371/journal.pcbi.1000925. PLoS Comput Biol. 2010. PMID: 20838579 Free PMC article.

2

Drug discovery in the age of systems biology: the rise of computational approaches for data integration.

Iskar M, Zeller G, Zhao XM, van Noort V, Bork P. Iskar M, et al. Curr Opin Biotechnol. 2012 Aug;23(4):609-16. doi: 10.1016/j.copbio.2011.11.010. Epub 2011 Dec 5. Curr Opin Biotechnol. 2012. PMID: 22153034 Review.

3

Prediction of drug combinations by integrating molecular and pharmacological data.

Zhao XM, Iskar M, Zeller G, Kuhn M, van Noort V, Bork P. Zhao XM, et al. Among authors: iskar m. PLoS Comput Biol. 2011 Dec;7(12):e1002323. doi: 10.1371/journal.pcbi.1002323. Epub 2011 Dec 29. PLoS Comput Biol. 2011. PMID: 22219721 Free PMC article.

4

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.

Iskar M, Zeller G, Blattmann P, Campillos M, Kuhn M, Kaminska KH, Runz H, Gavin AC, Pepperkok R, van Noort V, Bork P. Iskar M, et al. Mol Syst Biol. 2013;9:662. doi: 10.1038/msb.2013.20. Mol Syst Biol. 2013. PMID: 23632384 Free PMC article.

5

Network neighbors of drug targets contribute to drug side-effect similarity.

Brouwers L, Iskar M, Zeller G, van Noort V, Bork P. Brouwers L, et al. Among authors: iskar m. PLoS One. 2011;6(7):e22187. doi: 10.1371/journal.pone.0022187. Epub 2011 Jul 13. PLoS One. 2011. PMID: 21765950 Free PMC article.

6

Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling.

van Noort V, Schölch S, Iskar M, Zeller G, Ostertag K, Schweitzer C, Werner K, Weitz J, Koch M, Bork P. van Noort V, et al. Among authors: iskar m. Cancer Res. 2014 Oct 15;74(20):5690-9. doi: 10.1158/0008-5472.CAN-13-3540. Epub 2014 Jul 18. Cancer Res. 2014. PMID: 25038229 Free article.

7

DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data.

Pacini C, Iorio F, Gonçalves E, Iskar M, Klabunde T, Bork P, Saez-Rodriguez J. Pacini C, et al. Among authors: iskar m. Bioinformatics. 2013 Jan 1;29(1):132-4. doi: 10.1093/bioinformatics/bts656. Epub 2012 Nov 4. Bioinformatics. 2013. PMID: 23129297 Free PMC article.

8

CART-a chemical annotation retrieval toolkit.

Deghou S, Zeller G, Iskar M, Driessen M, Castillo M, van Noort V, Bork P. Deghou S, et al. Among authors: iskar m. Bioinformatics. 2016 Sep 15;32(18):2869-71. doi: 10.1093/bioinformatics/btw233. Epub 2016 Jun 2. Bioinformatics. 2016. PMID: 27256313 Free PMC article.

9

Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer.

Iskar M, Bork P, van Noort V. Iskar M, et al. Mol Cell Oncol. 2015 Feb 11;2(2):e975080. doi: 10.4161/23723556.2014.975080. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308430 Free PMC article.

10

Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).

Mackmull MT, Iskar M, Parca L, Singer S, Bork P, Ori A, Beck M. Mackmull MT, et al. Among authors: iskar m. Mol Cell Proteomics. 2015 May;14(5):1350-60. doi: 10.1074/mcp.M114.042499. Epub 2015 Mar 9. Mol Cell Proteomics. 2015. PMID: 25755299 Free PMC article.

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