Takeda S - Search Results

1

Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action.

Ridpath JR, Takeda S, Swenberg JA, Nakamura J. Ridpath JR, et al. Among authors: takeda s. Environ Mol Mutagen. 2011 Mar;52(2):153-60. doi: 10.1002/em.20595. Environ Mol Mutagen. 2011. PMID: 20839229 Free PMC article.

2

Incorporation of metabolic activation potentiates cyclophosphamide-induced DNA damage response in isogenic DT40 mutant cells.

Hashimoto K, Takeda S, Swenberg JA, Nakamura J. Hashimoto K, et al. Among authors: takeda s. Mutagenesis. 2015 Nov;30(6):821-8. doi: 10.1093/mutage/gev042. Epub 2015 Jun 17. Mutagenesis. 2015. PMID: 26085549 Free PMC article.

3

Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium.

Tian X, Patel K, Ridpath JR, Chen Y, Zhou YH, Neo D, Clement J, Takata M, Takeda S, Sale J, Wright FA, Swenberg JA, Nakamura J. Tian X, et al. Among authors: takeda s. PLoS One. 2016 Dec 1;11(12):e0167503. doi: 10.1371/journal.pone.0167503. eCollection 2016. PLoS One. 2016. PMID: 27907204 Free PMC article.

4

Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.

Ridpath JR, Nakamura A, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde JM, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA, Nakamura J. Ridpath JR, et al. Among authors: takeda s. Cancer Res. 2007 Dec 1;67(23):11117-22. doi: 10.1158/0008-5472.CAN-07-3028. Cancer Res. 2007. PMID: 18056434

5

Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS.

Pachkowski BF, Tano K, Afonin V, Elder RH, Takeda S, Watanabe M, Swenberg JA, Nakamura J. Pachkowski BF, et al. Among authors: takeda s. Mutat Res. 2009 Dec 1;671(1-2):93-9. doi: 10.1016/j.mrfmmm.2009.09.006. Epub 2009 Sep 22. Mutat Res. 2009. PMID: 19778542 Free PMC article.

6

FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells.

Asagoshi K, Tano K, Chastain PD 2nd, Adachi N, Sonoda E, Kikuchi K, Koyama H, Nagata K, Kaufman DG, Takeda S, Wilson SH, Watanabe M, Swenberg JA, Nakamura J. Asagoshi K, et al. Among authors: takeda s. Mol Cancer Res. 2010 Feb;8(2):204-15. doi: 10.1158/1541-7786.MCR-09-0253. Epub 2010 Feb 9. Mol Cancer Res. 2010. PMID: 20145043 Free PMC article.

7

Accumulation of true single strand breaks and AP sites in base excision repair deficient cells.

Luke AM, Chastain PD, Pachkowski BF, Afonin V, Takeda S, Kaufman DG, Swenberg JA, Nakamura J. Luke AM, et al. Among authors: takeda s. Mutat Res. 2010 Dec 10;694(1-2):65-71. doi: 10.1016/j.mrfmmm.2010.08.008. Epub 2010 Sep 17. Mutat Res. 2010. PMID: 20851134 Free PMC article.

8

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations.

Sharma V, Collins LB, Chen TH, Herr N, Takeda S, Sun W, Swenberg JA, Nakamura J. Sharma V, et al. Among authors: takeda s. Oncotarget. 2016 May 3;7(18):25377-90. doi: 10.18632/oncotarget.8298. Oncotarget. 2016. PMID: 27015367 Free PMC article.

9

Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.

Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, Swenberg JA, Nakamura J. Hashimoto K, et al. Among authors: takeda s. Oncotarget. 2016 Sep 13;7(37):59795-59808. doi: 10.18632/oncotarget.10928. Oncotarget. 2016. PMID: 27486975 Free PMC article.

10

Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms.

Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S. Saha LK, et al. Among authors: takeda s. Environ Mol Mutagen. 2018 Jul;59(6):529-538. doi: 10.1002/em.22201. Epub 2018 May 15. Environ Mol Mutagen. 2018. PMID: 29761828

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