Frank H - Search Results

1

1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.

Glatt H, Baasanjav-Gerber C, Schumacher F, Monien BH, Schreiner M, Frank H, Seidel A, Engst W. Glatt H, et al. Among authors: frank h. Chem Biol Interact. 2011 Jun 30;192(1-2):81-6. doi: 10.1016/j.cbi.2010.09.009. Epub 2010 Sep 21. Chem Biol Interact. 2011. PMID: 20846518

2

Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.

Schumacher F, Engst W, Monien BH, Florian S, Schnapper A, Steinhauser L, Albert K, Frank H, Seidel A, Glatt H. Schumacher F, et al. Among authors: frank h. Anal Chem. 2012 Jul 17;84(14):6256-62. doi: 10.1021/ac301436q. Epub 2012 Jul 3. Anal Chem. 2012. PMID: 22816785

3

Oxidation of alcohols and reduction of aldehydes derived from methyl- and dimethylpyrenes by cDNA-expressed human alcohol dehydrogenases.

Kollock R, Frank H, Seidel A, Meinl W, Glatt H. Kollock R, et al. Among authors: frank h. Toxicology. 2008 Mar 12;245(1-2):65-75. doi: 10.1016/j.tox.2007.12.012. Epub 2007 Dec 23. Toxicology. 2008. PMID: 18242813

4

Conversion of the common food constituent 5-hydroxymethylfurfural into a mutagenic and carcinogenic sulfuric acid ester in the mouse in vivo.

Monien BH, Frank H, Seidel A, Glatt H. Monien BH, et al. Among authors: frank h. Chem Res Toxicol. 2009 Jun;22(6):1123-8. doi: 10.1021/tx9000623. Chem Res Toxicol. 2009. PMID: 19382817

5

Renal organic anion transporters OAT1 and OAT3 mediate the cellular accumulation of 5-sulfooxymethylfurfural, a reactive, nephrotoxic metabolite of the Maillard product 5-hydroxymethylfurfural.

Bakhiya N, Monien B, Frank H, Seidel A, Glatt H. Bakhiya N, et al. Among authors: frank h. Biochem Pharmacol. 2009 Aug 15;78(4):414-9. doi: 10.1016/j.bcp.2009.04.017. Epub 2009 Apr 24. Biochem Pharmacol. 2009. PMID: 19394312 Free article.

6

Probenecid, an inhibitor of transmembrane organic anion transporters, alters tissue distribution of DNA adducts in 1-hydroxymethylpyrene-treated rats.

Monien BH, Müller C, Bakhiya N, Donath C, Frank H, Seidel A, Glatt H. Monien BH, et al. Among authors: frank h. Toxicology. 2009 Jul 28;262(1):80-5. doi: 10.1016/j.tox.2009.05.016. Epub 2009 May 27. Toxicology. 2009. PMID: 19481134

7

Directing role of organic anion transporters in the excretion of mercapturic acids of alkylated polycyclic aromatic hydrocarbons.

Bakhiya N, Batke M, Laake J, Monien BH, Frank H, Seidel A, Engst W, Glatt H. Bakhiya N, et al. Among authors: frank h. Drug Metab Dispos. 2007 Oct;35(10):1824-31. doi: 10.1124/dmd.107.016964. Epub 2007 Jul 16. Drug Metab Dispos. 2007. PMID: 17639024

8

Efficient oxidation of promutagenic hydroxymethylpyrenes by cDNA-expressed human alcohol dehydrogenase ADH2 and its inhibition by various agents.

Kollock R, Meinl W, Schneider H, Batke M, Frank H, Seidel A, Glatt H. Kollock R, et al. Among authors: frank h. Biochem Pharmacol. 2008 Jan 15;75(2):527-37. doi: 10.1016/j.bcp.2007.08.030. Epub 2007 Sep 1. Biochem Pharmacol. 2008. PMID: 17920042

9

Detoxification of promutagenic aldehydes derived from methylpyrenes by human aldehyde dehydrogenases ALDH2 and ALDH3A1.

Glatt H, Rost K, Frank H, Seidel A, Kollock R. Glatt H, et al. Among authors: frank h. Arch Biochem Biophys. 2008 Sep 15;477(2):196-205. doi: 10.1016/j.abb.2008.06.020. Epub 2008 Jun 28. Arch Biochem Biophys. 2008. PMID: 18621017

10

Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling.

Monien BH, Müller C, Engst W, Frank H, Seidel A, Glatt H. Monien BH, et al. Among authors: frank h. Chem Res Toxicol. 2008 Oct;21(10):2017-25. doi: 10.1021/tx800217d. Epub 2008 Sep 13. Chem Res Toxicol. 2008. PMID: 18788758

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