Kaufman RJ - Search Results

1

In vivo efficacy of platelet-delivered, high specific activity factor VIII variants.

Greene TK, Wang C, Hirsch JD, Zhai L, Gewirtz J, Thornton MA, Miao HZ, Pipe SW, Kaufman RJ, Camire RM, Arruda VR, Kowalska MA, Poncz M. Greene TK, et al. Among authors: kaufman rj. Blood. 2010 Dec 23;116(26):6114-22. doi: 10.1182/blood-2010-06-293308. Epub 2010 Sep 17. Blood. 2010. PMID: 20852129 Free PMC article.

2

Bioengineering of coagulation factor VIII for improved secretion.

Miao HZ, Sirachainan N, Palmer L, Kucab P, Cunningham MA, Kaufman RJ, Pipe SW. Miao HZ, et al. Among authors: kaufman rj. Blood. 2004 May 1;103(9):3412-9. doi: 10.1182/blood-2003-10-3591. Epub 2004 Jan 15. Blood. 2004. PMID: 14726380 Free article.

3

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.

Gilbert GE, Novakovic VA, Kaufman RJ, Miao H, Pipe SW. Gilbert GE, et al. Among authors: kaufman rj. Blood. 2012 Aug 30;120(9):1923-32. doi: 10.1182/blood-2012-01-408245. Epub 2012 May 21. Blood. 2012. PMID: 22613792 Free PMC article.

4

Correction of murine hemophilia A and immunological differences of factor VIII variants delivered by helper-dependent adenoviral vectors.

Cerullo V, Seiler MP, Mane V, Cela R, Clarke C, Kaufman RJ, Pipe SW, Lee B. Cerullo V, et al. Among authors: kaufman rj. Mol Ther. 2007 Dec;15(12):2080-7. doi: 10.1038/sj.mt.6300308. Epub 2007 Sep 11. Mol Ther. 2007. PMID: 17848960 Free article.

5

Mild hemophilia A caused by increased rate of factor VIII A2 subunit dissociation: evidence for nonproteolytic inactivation of factor VIIIa in vivo.

Pipe SW, Eickhorst AN, McKinley SH, Saenko EL, Kaufman RJ. Pipe SW, et al. Among authors: kaufman rj. Blood. 1999 Jan 1;93(1):176-83. Blood. 1999. PMID: 9864159 Free article.

6

Can we improve on nature? "Super molecules" of factor VIII.

Kaufman RJ, Pipe SW. Kaufman RJ, et al. Haemophilia. 1998 Jul;4(4):370-9. doi: 10.1046/j.1365-2516.1998.440370.x. Haemophilia. 1998. PMID: 9873757 Free article. Review.

7

Regulation of factor VIII expression and activity by von Willebrand factor.

Kaufman RJ, Pipe SW. Kaufman RJ, et al. Thromb Haemost. 1999 Aug;82(2):201-8. Thromb Haemost. 1999. PMID: 10605705 Review. No abstract available.

8

Factor VIII C2 domain missense mutations exhibit defective trafficking of biologically functional proteins.

Pipe SW, Kaufman RJ. Pipe SW, et al. Among authors: kaufman rj. J Biol Chem. 1996 Oct 11;271(41):25671-6. doi: 10.1074/jbc.271.41.25671. J Biol Chem. 1996. PMID: 8810344 Free article.

9

Hemophilia A mutations associated with 1-stage/2-stage activity discrepancy disrupt protein-protein interactions within the triplicated A domains of thrombin-activated factor VIIIa.

Pipe SW, Saenko EL, Eickhorst AN, Kemball-Cook G, Kaufman RJ. Pipe SW, et al. Among authors: kaufman rj. Blood. 2001 Feb 1;97(3):685-91. doi: 10.1182/blood.v97.3.685. Blood. 2001. PMID: 11157485 Free article.

10

Bioengineering of coagulation factor VIII for efficient expression through elimination of a dispensable disulfide loop.

Selvaraj SR, Scheller AN, Miao HZ, Kaufman RJ, Pipe SW. Selvaraj SR, et al. Among authors: kaufman rj. J Thromb Haemost. 2012 Jan;10(1):107-15. doi: 10.1111/j.1538-7836.2011.04545.x. J Thromb Haemost. 2012. PMID: 22044596 Free PMC article.

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