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Phase 1 trial of IL-15 trans presentation blockade using humanized Mikβ1 mAb in patients with T-cell large granular lymphocytic leukemia.
Waldmann TA, Conlon KC, Stewart DM, Worthy TA, Janik JE, Fleisher TA, Albert PS, Figg WD, Spencer SD, Raffeld M, Decker JR, Goldman CK, Bryant BR, Petrus MN, Creekmore SP, Morris JC. Waldmann TA, et al. Among authors: petrus mn. Blood. 2013 Jan 17;121(3):476-84. doi: 10.1182/blood-2012-08-450585. Epub 2012 Dec 3. Blood. 2013. PMID: 23212516 Free PMC article. Clinical Trial.
Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma.
Ishio T, Kumar S, Shimono J, Daenthanasanmak A, Dubois S, Lin Y, Bryant B, Petrus MN, Bachy E, Huang DW, Yang Y, Green PL, Hasegawa H, Maeda M, Goto H, Endo T, Yokota T, Hatanaka KC, Hatanaka Y, Tanaka S, Matsuno Y, Yang Y, Hashino S, Teshima T, Waldmann TA, Staudt LM, Nakagawa M. Ishio T, et al. Among authors: petrus mn. Blood. 2022 Mar 10;139(10):1541-1556. doi: 10.1182/blood.2021012734. Blood. 2022. PMID: 34818414 Free PMC article.
Preclinical and phase I clinical trial of blockade of IL-15 using Mikbeta1 monoclonal antibody in T cell large granular lymphocyte leukemia.
Morris JC, Janik JE, White JD, Fleisher TA, Brown M, Tsudo M, Goldman CK, Bryant B, Petrus M, Top L, Lee CC, Gao W, Waldmann TA. Morris JC, et al. Among authors: petrus m. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):401-6. doi: 10.1073/pnas.0509575103. Epub 2005 Dec 30. Proc Natl Acad Sci U S A. 2006. PMID: 16387851 Free PMC article. Clinical Trial.
A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling.
Nguyen VP, Chen J, Petrus MN, Goldman CK, Kruhlak MJ, Bamford RN, Waldmann TA. Nguyen VP, et al. J Innate Immun. 2014;6(3):377-93. doi: 10.1159/000356408. Epub 2014 Feb 26. J Innate Immun. 2014. PMID: 24577058 Free PMC article.
146 results