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Page 1
The perforin pore facilitates the delivery of cationic cargos.
Stewart SE, Kondos SC, Matthews AY, D'Angelo ME, Dunstone MA, Whisstock JC, Trapani JA, Bird PI. Stewart SE, et al. Among authors: kondos sc. J Biol Chem. 2014 Mar 28;289(13):9172-81. doi: 10.1074/jbc.M113.544890. Epub 2014 Feb 20. J Biol Chem. 2014. PMID: 24558045 Free PMC article.
Conformational changes during pore formation by the perforin-related protein pleurotolysin.
Lukoyanova N, Kondos SC, Farabella I, Law RH, Reboul CF, Caradoc-Davies TT, Spicer BA, Kleifeld O, Traore DA, Ekkel SM, Voskoboinik I, Trapani JA, Hatfaludi T, Oliver K, Hotze EM, Tweten RK, Whisstock JC, Topf M, Saibil HR, Dunstone MA. Lukoyanova N, et al. Among authors: kondos sc. PLoS Biol. 2015 Feb 5;13(2):e1002049. doi: 10.1371/journal.pbio.1002049. eCollection 2015 Feb. PLoS Biol. 2015. PMID: 25654333 Free PMC article.
Structure of the poly-C9 component of the complement membrane attack complex.
Dudkina NV, Spicer BA, Reboul CF, Conroy PJ, Lukoyanova N, Elmlund H, Law RH, Ekkel SM, Kondos SC, Goode RJ, Ramm G, Whisstock JC, Saibil HR, Dunstone MA. Dudkina NV, et al. Among authors: kondos sc. Nat Commun. 2016 Feb 4;7:10588. doi: 10.1038/ncomms10588. Nat Commun. 2016. PMID: 26841934 Free PMC article.
The MACPF/CDC family of pore-forming toxins.
Rosado CJ, Kondos S, Bull TE, Kuiper MJ, Law RH, Buckle AM, Voskoboinik I, Bird PI, Trapani JA, Whisstock JC, Dunstone MA. Rosado CJ, et al. Cell Microbiol. 2008 Sep;10(9):1765-74. doi: 10.1111/j.1462-5822.2008.01191.x. Epub 2008 Jun 28. Cell Microbiol. 2008. PMID: 18564372 Free PMC article. Review.
Real-time visualization of perforin nanopore assembly.
Leung C, Hodel AW, Brennan AJ, Lukoyanova N, Tran S, House CM, Kondos SC, Whisstock JC, Dunstone MA, Trapani JA, Voskoboinik I, Saibil HR, Hoogenboom BW. Leung C, et al. Among authors: kondos sc. Nat Nanotechnol. 2017 May;12(5):467-473. doi: 10.1038/nnano.2016.303. Epub 2017 Feb 6. Nat Nanotechnol. 2017. PMID: 28166206