Trapani JA - Search Results

1

The structure and function of mammalian membrane-attack complex/perforin-like proteins.

Kondos SC, Hatfaludi T, Voskoboinik I, Trapani JA, Law RH, Whisstock JC, Dunstone MA. Kondos SC, et al. Among authors: trapani ja. Tissue Antigens. 2010 Nov;76(5):341-51. doi: 10.1111/j.1399-0039.2010.01566.x. Epub 2010 Sep 22. Tissue Antigens. 2010. PMID: 20860583 Review.

2

Novel putative promoter/enhancer sequences are shared by the mouse and human perforin (Pfp) genes.

Trapani JA, Dupont B. Trapani JA, et al. Tissue Antigens. 1990 Nov;36(5):228-34. doi: 10.1111/j.1399-0039.1990.tb01833.x. Tissue Antigens. 1990. PMID: 2095003

3

The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene.

Voskoboinik I, Thia MC, De Bono A, Browne K, Cretney E, Jackson JT, Darcy PK, Jane SM, Smyth MJ, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. J Exp Med. 2004 Sep 20;200(6):811-6. doi: 10.1084/jem.20040776. Epub 2004 Sep 14. J Exp Med. 2004. PMID: 15365097 Free PMC article.

4

Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

Voskoboinik I, Thia MC, Fletcher J, Ciccone A, Browne K, Smyth MJ, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. J Biol Chem. 2005 Mar 4;280(9):8426-34. doi: 10.1074/jbc.M413303200. Epub 2004 Dec 2. J Biol Chem. 2005. PMID: 15576364 Free article.

5

A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis.

Voskoboinik I, Thia MC, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. Blood. 2005 Jun 15;105(12):4700-6. doi: 10.1182/blood-2004-12-4935. Epub 2005 Mar 8. Blood. 2005. PMID: 15755897 Free article.

6

Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells.

Bird CH, Sun J, Ung K, Karambalis D, Whisstock JC, Trapani JA, Bird PI. Bird CH, et al. Among authors: trapani ja. Mol Cell Biol. 2005 Sep;25(17):7854-67. doi: 10.1128/MCB.25.17.7854-7867.2005. Mol Cell Biol. 2005. PMID: 16107729 Free PMC article.

7

Addressing the mysteries of perforin function.

Voskoboinik I, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. Immunol Cell Biol. 2006 Feb;84(1):66-71. doi: 10.1111/j.1440-1711.2005.01409.x. Immunol Cell Biol. 2006. PMID: 16405653 Review.

8

The major human and mouse granzymes are structurally and functionally divergent.

Kaiserman D, Bird CH, Sun J, Matthews A, Ung K, Whisstock JC, Thompson PE, Trapani JA, Bird PI. Kaiserman D, et al. Among authors: trapani ja. J Cell Biol. 2006 Nov 20;175(4):619-30. doi: 10.1083/jcb.200606073. J Cell Biol. 2006. PMID: 17116752 Free PMC article.

9

Perforin-mediated target-cell death and immune homeostasis.

Voskoboinik I, Smyth MJ, Trapani JA. Voskoboinik I, et al. Among authors: trapani ja. Nat Rev Immunol. 2006 Dec;6(12):940-52. doi: 10.1038/nri1983. Nat Rev Immunol. 2006. PMID: 17124515 Review.

10

Apoptosis induced by the lymphocyte effector molecule perforin.

Bolitho P, Voskoboinik I, Trapani JA, Smyth MJ. Bolitho P, et al. Among authors: trapani ja. Curr Opin Immunol. 2007 Jun;19(3):339-47. doi: 10.1016/j.coi.2007.04.007. Epub 2007 Apr 17. Curr Opin Immunol. 2007. PMID: 17442557 Review.

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