Madsen AS - Search Results

1

Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA.

Zaghloul EM, Madsen AS, Moreno PM, Oprea II, El-Andaloussi S, Bestas B, Gupta P, Pedersen EB, Lundin KE, Wengel J, Smith CI. Zaghloul EM, et al. Among authors: madsen as. Nucleic Acids Res. 2011 Feb;39(3):1142-54. doi: 10.1093/nar/gkq835. Epub 2010 Sep 21. Nucleic Acids Res. 2011. PMID: 20860997 Free PMC article.

2

LNA 5'-phosphoramidites for 5'→3'-oligonucleotide synthesis.

Madsen AS, Kumar TS, Wengel J. Madsen AS, et al. Org Biomol Chem. 2010 Nov 7;8(21):5012-6. doi: 10.1039/c0ob00346h. Epub 2010 Sep 3. Org Biomol Chem. 2010. PMID: 20820663

3

Functionalization of 2'-amino-LNA with additional nucleobases.

Umemoto T, Wengel J, Madsen AS. Umemoto T, et al. Among authors: madsen as. Org Biomol Chem. 2009 May 7;7(9):1793-7. doi: 10.1039/b901028a. Epub 2009 Mar 19. Org Biomol Chem. 2009. PMID: 19590773

4

Oligonucleotides with 1,4-dioxane-based nucleotide monomers.

Madsen AS, Wengel J. Madsen AS, et al. J Org Chem. 2012 Apr 20;77(8):3878-86. doi: 10.1021/jo300222q. Epub 2012 Apr 2. J Org Chem. 2012. PMID: 22439826

5

Nucleosides with 1,4-dioxane as sugar moiety.

Madsen AS, Langkjaer N, Wengel J. Madsen AS, et al. Nucleic Acids Symp Ser (Oxf). 2008;(52):269-70. doi: 10.1093/nass/nrn136. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776357

6

Enzymatic polymerisation involving 2'-amino-LNA nucleotides.

Johannsen MW, Veedu RN, Madsen AS, Wengel J. Johannsen MW, et al. Among authors: madsen as. Bioorg Med Chem Lett. 2012 May 15;22(10):3522-6. doi: 10.1016/j.bmcl.2012.03.073. Epub 2012 Mar 28. Bioorg Med Chem Lett. 2012. PMID: 22503454

7

Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3'-O,4'-C-methylene-linked alpha-L-ribonucleotides.

Madsen AS, Hrdlicka PJ, Kumar TS, Wengel J. Madsen AS, et al. Carbohydr Res. 2006 Jul 24;341(10):1398-407. doi: 10.1016/j.carres.2006.04.010. Epub 2006 May 18. Carbohydr Res. 2006. PMID: 16709404

8

Effective modulation of DNA duplex stability by reversible transition metal complex formation in the minor groove.

Kalek M, Madsen AS, Wengel J. Kalek M, et al. Among authors: madsen as. J Am Chem Soc. 2007 Aug 1;129(30):9392-400. doi: 10.1021/ja071076z. Epub 2007 Jul 7. J Am Chem Soc. 2007. PMID: 17616191

9

Synthesis and biophysical studies of N2'-functionalized 2'-amino-alpha-L-LNA.

Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ. Kumar TS, et al. Among authors: madsen as. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1403-5. doi: 10.1080/15257770701538841. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066792

10

Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.

Kumar TS, Madsen AS, Østergaard ME, Sau SP, Wengel J, Hrdlicka PJ. Kumar TS, et al. Among authors: madsen as. J Org Chem. 2009 Feb 6;74(3):1070-81. doi: 10.1021/jo802037v. J Org Chem. 2009. PMID: 19108636 Free PMC article.

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