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The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells.
Cosker F, Cheviron N, Yamasaki M, Menteyne A, Lund FE, Moutin MJ, Galione A, Cancela JM. Cosker F, et al. Among authors: moutin mj. J Biol Chem. 2010 Dec 3;285(49):38251-9. doi: 10.1074/jbc.M110.125864. Epub 2010 Sep 24. J Biol Chem. 2010. PMID: 20870729 Free PMC article.
A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate.
Ramakrishnan L, Muller-Steffner H, Bosc C, Vacquier VD, Schuber F, Moutin MJ, Dale L, Patel S. Ramakrishnan L, et al. Among authors: moutin mj. J Biol Chem. 2010 Jun 25;285(26):19900-9. doi: 10.1074/jbc.M110.105312. Epub 2010 Apr 12. J Biol Chem. 2010. PMID: 20385553 Free PMC article.
49 results