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Page 1
Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity.
Alvarez G, Aguirre-López B, Varela J, Cabrera M, Merlino A, López GV, Lavaggi ML, Porcal W, Di Maio R, González M, Cerecetto H, Cabrera N, Pérez-Montfort R, de Gómez-Puyou MT, Gómez-Puyou A. Alvarez G, et al. Among authors: di maio r. Eur J Med Chem. 2010 Dec;45(12):5767-72. doi: 10.1016/j.ejmech.2010.09.034. Epub 2010 Sep 19. Eur J Med Chem. 2010. PMID: 20889239
Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.
Aguirre G, Cabrera E, Cerecetto H, Di Maio R, González M, Seoane G, Duffaut A, Denicola A, Gil MJ, Martínez-Merino V. Aguirre G, et al. Among authors: di maio r. Eur J Med Chem. 2004 May;39(5):421-31. doi: 10.1016/j.ejmech.2004.02.007. Eur J Med Chem. 2004. PMID: 15110968
Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Part 3: Substituents-clustering methodology in the search for new active compounds.
Aguirre G, Boiani L, Cerecetto H, Di Maio R, González M, Porcal W, Denicola A, Möller M, Thomson L, Tórtora V. Aguirre G, et al. Among authors: di maio r. Bioorg Med Chem. 2005 Dec 1;13(23):6324-35. doi: 10.1016/j.bmc.2005.05.020. Epub 2005 Aug 22. Bioorg Med Chem. 2005. PMID: 16115774
5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: preliminary in vivo studies.
Cabrera E, Murguiondo MG, Arias MG, Arredondo C, Pintos C, Aguirre G, Fernández M, Basmadjián Y, Rosa R, Pacheco JP, Raymondo S, Di Maio R, González M, Cerecetto H. Cabrera E, et al. Among authors: di maio r. Eur J Med Chem. 2009 Oct;44(10):3909-14. doi: 10.1016/j.ejmech.2009.04.015. Epub 2009 Apr 14. Eur J Med Chem. 2009. PMID: 19446929
3-Trifluoromethylquinoxaline N,N'-dioxides as anti-trypanosomatid agents. Identification of optimal anti-T. cruzi agents and mechanism of action studies.
Benitez D, Cabrera M, Hernández P, Boiani L, Lavaggi ML, Di Maio R, Yaluff G, Serna E, Torres S, Ferreira ME, Vera de Bilbao N, Torres E, Pérez-Silanes S, Solano B, Moreno E, Aldana I, López de Ceráin A, Cerecetto H, González M, Monge A. Benitez D, et al. Among authors: di maio r. J Med Chem. 2011 May 26;54(10):3624-36. doi: 10.1021/jm2002469. Epub 2011 May 4. J Med Chem. 2011. PMID: 21506600
Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents.
Torres E, Moreno-Viguri E, Galiano S, Devarapally G, Crawford PW, Azqueta A, Arbillaga L, Varela J, Birriel E, Di Maio R, Cerecetto H, González M, Aldana I, Monge A, Pérez-Silanes S. Torres E, et al. Among authors: di maio r. Eur J Med Chem. 2013 Aug;66:324-34. doi: 10.1016/j.ejmech.2013.04.065. Epub 2013 May 30. Eur J Med Chem. 2013. PMID: 23811257 Free article.
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