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A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice.
Case JB, Sanapala S, Dillen C, Rhodes V, Zmasek C, Chicz TM, Switzer CE, Scheaffer SM, Georgiev G, Jacob-Dolan C, Hauser BM, Dos Anjos DCC, Adams LJ, Soudani N, Liang CY, Ying B, McNamara RP, Scheuermann RH, Boon ACM, Fremont DH, Whelan SPJ, Schmidt AG, Sette A, Grifoni A, Frieman MB, Diamond MS. Case JB, et al. Among authors: adams lj. Cell Host Microbe. 2024 Dec 11;32(12):2131-2147.e8. doi: 10.1016/j.chom.2024.10.016. Epub 2024 Nov 18. Cell Host Microbe. 2024. PMID: 39561781 Free article.
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone.
Dunn ME, Kithcart A, Kim JH, Ho AJ, Franklin MC, Romero Hernandez A, de Hoon J, Botermans W, Meyer J, Jin X, Zhang D, Torello J, Jasewicz D, Kamat V, Garnova E, Liu N, Rosconi M, Pan H, Karnik S, Burczynski ME, Zheng W, Rafique A, Nielsen JB, De T, Verweij N, Pandit A, Locke A, Chalasani N, Melander O, Schwantes-An TH; Penn Medicine Biobank; Baras A, Lotta LA, Musser BJ, Mastaitis J, Devalaraja-Narashimha KB, Rankin AJ, Huang T, Herman G, Olson W, Murphy AJ, Yancopoulos GD, Olenchock BA, Morton L. Dunn ME, et al. Nature. 2024 Sep;633(8030):654-661. doi: 10.1038/s41586-024-07903-1. Epub 2024 Sep 11. Nature. 2024. PMID: 39261724 Free PMC article. Clinical Trial.
Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity.
Zimmerman O, Altman Doss AM, Ying B, Liang CY, Mackin SR, Davis-Adams HG, Adams LJ, VanBlargan LA, Chen RE, Scheaffer SM, Desai P, Raju S, Mantia TL, O'Shaughnessy CC, Monroy JM, Wedner HJ, Rigell CJ, Kau AL, Dy TB, Ren Z, Turner JS, O'Halloran JA, Presti RM, Kendall PL, Fremont DH, Ellebedy AH, Diamond MS. Zimmerman O, et al. Among authors: adams lj. JCI Insight. 2024 Feb 8;9(3):e176359. doi: 10.1172/jci.insight.176359. JCI Insight. 2024. PMID: 38175703 Free PMC article.
The many ways in which alphaviruses bind to cells.
Raju S, Adams LJ, Diamond MS. Raju S, et al. Among authors: adams lj. Trends Immunol. 2024 Feb;45(2):85-93. doi: 10.1016/j.it.2023.11.006. Epub 2023 Dec 22. Trends Immunol. 2024. PMID: 38135598 Free PMC article. Review.
CD62L expression marks a functionally distinct subset of memory B cells.
Hanson CH, Henry B, Andhare P, Lin FJ, Pak H, Turner JS, Adams LJ, Liu T, Fremont DH, Ellebedy AH, Laidlaw BJ. Hanson CH, et al. Among authors: adams lj. Cell Rep. 2023 Dec 26;42(12):113542. doi: 10.1016/j.celrep.2023.113542. Epub 2023 Dec 5. Cell Rep. 2023. PMID: 38060451 Free PMC article.
92 results