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Page 1
Towards the discovery of new hypnotic agents: synthesis and preliminary pharmacological evaluation of a novel class of dibenzo[a,d]cycloheptene derivatives.
Castiglioni E, Di Fabio R, Togninelli A, Brough S, Brown F, Dal Cin M, Gianotti M, Marchioro C, Merlo G, Spinosa R, Wigglesworth MJ, Botta M. Castiglioni E, et al. Among authors: brown f. ChemMedChem. 2010 Nov 8;5(11):1843-6. doi: 10.1002/cmdc.201000280. ChemMedChem. 2010. PMID: 20922744 No abstract available.
The identification of novel orally active mGluR5 antagonist GSK2210875.
Pilla M, Andreoli M, Tessari M, Delle-Fratte S, Roth A, Butler S, Brown F, Shah P, Bettini E, Cavallini P, Benedetti R, Minick D, Smith P, Tehan B, D'Alessandro P, Lorthioir O, Ball C, Garzya V, Goodacre C, Watson S. Pilla M, et al. Among authors: brown f. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7521-4. doi: 10.1016/j.bmcl.2010.09.120. Epub 2010 Nov 2. Bioorg Med Chem Lett. 2010. PMID: 21051228
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.
Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Drewes G, Eagle R, Garton N, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, Katso R, Kruidenier L, Leveridge M, Pemberton M, Rioja I, Seal GA, Shipley T, Singh O, Suckling CJ, Taylor J, Thomas P, Wilson DM, Lee K, Prinjha RK. Westaway SM, et al. Among authors: brown f, brown ja. J Med Chem. 2016 Feb 25;59(4):1370-87. doi: 10.1021/acs.jmedchem.5b01538. Epub 2016 Jan 15. J Med Chem. 2016. PMID: 26771203
Configuration of a high-content imaging platform for hit identification and pharmacological assessment of JMJD3 demethylase enzyme inhibitors.
Mulji A, Haslam C, Brown F, Randle R, Karamshi B, Smith J, Eagle R, Munoz-Muriedas J, Taylor J, Sheikh A, Bridges A, Gill K, Jepras R, Smee P, Barker M, Woodrow M, Liddle J, Thomas P, Jones E, Gordon L, Tanner R, Leveridge M, Hutchinson S, Martin M, Brown M, Kruidenier L, Katso R. Mulji A, et al. Among authors: brown f, brown m. J Biomol Screen. 2012 Jan;17(1):108-20. doi: 10.1177/1087057111418229. J Biomol Screen. 2012. PMID: 22223398
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Diallo H, Douault C, Drewes G, Eagle R, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, Katso R, Kruidenier L, Leveridge M, Liddle J, Mosley J, Muelbaier M, Randle R, Rioja I, Rueger A, Seal GA, Sheppard RJ, Singh O, Taylor J, Thomas P, Thomson D, Wilson DM, Lee K, Prinjha RK. Westaway SM, et al. Among authors: brown f, brown ja. J Med Chem. 2016 Feb 25;59(4):1357-69. doi: 10.1021/acs.jmedchem.5b01537. Epub 2016 Jan 15. J Med Chem. 2016. PMID: 26771107
Cardiac arrhythmia assessment with patch electrocardiogram versus insertable cardiac monitor: a cohort study in endurance athletes with atrial fibrillation.
Apelland T, Sellevold AB, Letnes JM, Onarheim S, Enger S, Tveit A, Delpire B, Claessen G, La Gerche A, Loennechen JP, Berge T, Myrstad M; NEXAF Investigators; NEXAF investigators. Apelland T, et al. BMJ Open. 2025 Jan 6;15(1):e093250. doi: 10.1136/bmjopen-2024-093250. BMJ Open. 2025. PMID: 39762092 Free article.
The effects of plasma exchange and glucocorticoids on early kidney function among patients with ANCA-associated vasculitis in the PEXIVAS trial.
Odler B, Riedl R, Geetha D, Szpirt WM, Hawley C, Uchida L, Wallace ZS, Walters G, Muso E, Tesar V, Pusey CD, Little MA, Merkel PA, Walsh M, Jayne DRW, Kronbichler A; PEXIVAS Investigators. Odler B, et al. Kidney Int. 2024 Dec 19:S0085-2538(24)00911-6. doi: 10.1016/j.kint.2024.11.029. Online ahead of print. Kidney Int. 2024. PMID: 39708998 Free article.
1,804 results