O'Gorman WE - Search Results

1

Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling.

Sathaliyawala T, O'Gorman WE, Greter M, Bogunovic M, Konjufca V, Hou ZE, Nolan GP, Miller MJ, Merad M, Reizis B. Sathaliyawala T, et al. Immunity. 2010 Oct 29;33(4):597-606. doi: 10.1016/j.immuni.2010.09.012. Epub 2010 Oct 7. Immunity. 2010. PMID: 20933441 Free PMC article.

2

The initial phase of an immune response functions to activate regulatory T cells.

O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, Nolan GP, Abbas AK. O'Gorman WE, et al. J Immunol. 2009 Jul 1;183(1):332-9. doi: 10.4049/jimmunol.0900691. J Immunol. 2009. PMID: 19542444 Free PMC article.

3

Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses.

O'Gorman WE, Sampath P, Simonds EF, Sikorski R, O'Malley M, Krutzik PO, Chen H, Panchanathan V, Chaudhri G, Karupiah G, Lewis DB, Thorne SH, Nolan GP. O'Gorman WE, et al. Cell Host Microbe. 2010 Aug 19;8(2):174-85. doi: 10.1016/j.chom.2010.07.008. Cell Host Microbe. 2010. PMID: 20709294 Free PMC article.

4

Duration of antigen receptor signaling determines T-cell tolerance or activation.

Katzman SD, O'Gorman WE, Villarino AV, Gallo E, Friedman RS, Krummel MF, Nolan GP, Abbas AK. Katzman SD, et al. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18085-90. doi: 10.1073/pnas.1010560107. Epub 2010 Oct 4. Proc Natl Acad Sci U S A. 2010. PMID: 20921406 Free PMC article.

5

Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus.

O'Gorman WE, Hsieh EW, Savig ES, Gherardini PF, Hernandez JD, Hansmann L, Balboni IM, Utz PJ, Bendall SC, Fantl WJ, Lewis DB, Nolan GP, Davis MM. O'Gorman WE, et al. J Allergy Clin Immunol. 2015 Nov;136(5):1326-36. doi: 10.1016/j.jaci.2015.04.008. Epub 2015 May 30. J Allergy Clin Immunol. 2015. PMID: 26037552 Free PMC article.

6

Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients.

O'Gorman WE, Kong DS, Balboni IM, Rudra P, Bolen CR, Ghosh D, Davis MM, Nolan GP, Hsieh EW. O'Gorman WE, et al. J Autoimmun. 2017 Apr 4:S0896-8411(16)30412-7. doi: 10.1016/j.jaut.2017.03.010. Online ahead of print. J Autoimmun. 2017. PMID: 28389038 Free PMC article.

7

The potential functions of primary microRNAs in target recognition and repression.

Trujillo RD, Yue SB, Tang Y, O'Gorman WE, Chen CZ. Trujillo RD, et al. EMBO J. 2010 Oct 6;29(19):3272-85. doi: 10.1038/emboj.2010.208. Epub 2010 Aug 31. EMBO J. 2010. PMID: 20808284 Free PMC article.

8

Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8⁺ T cell responses.

Banta KL, Xu X, Chitre AS, Au-Yeung A, Takahashi C, O'Gorman WE, Wu TD, Mittman S, Cubas R, Comps-Agrar L, Fulzele A, Bennett EJ, Grogan JL, Hui E, Chiang EY, Mellman I. Banta KL, et al. Among authors: o gorman we. Immunity. 2022 Mar 8;55(3):512-526.e9. doi: 10.1016/j.immuni.2022.02.005. Immunity. 2022. PMID: 35263569 Free PMC article.

9

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells.

Barron L, Dooms H, Hoyer KK, Kuswanto W, Hofmann J, O'Gorman WE, Abbas AK. Barron L, et al. J Immunol. 2010 Dec 1;185(11):6426-30. doi: 10.4049/jimmunol.0903940. Epub 2010 Oct 29. J Immunol. 2010. PMID: 21037099 Free PMC article.

10

Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963.

Thorne SH, Hwang TH, O'Gorman WE, Bartlett DL, Sei S, Kanji F, Brown C, Werier J, Cho JH, Lee DE, Wang Y, Bell J, Kirn DH. Thorne SH, et al. J Clin Invest. 2007 Nov;117(11):3350-8. doi: 10.1172/JCI32727. J Clin Invest. 2007. PMID: 17965776 Free PMC article.

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