Botta M - Search Results

1

Novel spirotetracyclic zwitterionic dual H(1)/5-HT(2A) receptor antagonists for the treatment of sleep disorders.

Gianotti M, Botta M, Brough S, Carletti R, Castiglioni E, Corti C, Dal-Cin M, Delle Fratte S, Korajac D, Lovric M, Merlo G, Mesic M, Pavone F, Piccoli L, Rast S, Roscic M, Sava A, Smehil M, Stasi L, Togninelli A, Wigglesworth MJ. Gianotti M, et al. Among authors: botta m. J Med Chem. 2010 Nov 11;53(21):7778-95. doi: 10.1021/jm100856p. J Med Chem. 2010. PMID: 20942472

2

Towards the discovery of new hypnotic agents: synthesis and preliminary pharmacological evaluation of a novel class of dibenzo[a,d]cycloheptene derivatives.

Castiglioni E, Di Fabio R, Togninelli A, Brough S, Brown F, Dal Cin M, Gianotti M, Marchioro C, Merlo G, Spinosa R, Wigglesworth MJ, Botta M. Castiglioni E, et al. Among authors: botta m. ChemMedChem. 2010 Nov 8;5(11):1843-6. doi: 10.1002/cmdc.201000280. ChemMedChem. 2010. PMID: 20922744 No abstract available.

3

Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.

Mugnaini C, Alongi M, Togninelli A, Gevariya H, Brizzi A, Manetti F, Bernardini C, Angeli L, Tafi A, Bellucci L, Corelli F, Massa S, Maga G, Samuele A, Facchini M, Clotet-Codina I, Armand-Ugón M, Esté JA, Botta M. Mugnaini C, et al. Among authors: botta m. J Med Chem. 2007 Dec 27;50(26):6580-95. doi: 10.1021/jm0708230. Epub 2007 Dec 6. J Med Chem. 2007. PMID: 18052319

4

Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity.

Manetti F, Esté JA, Clotet-Codina I, Armand-Ugón M, Maga G, Crespan E, Cancio R, Mugnaini C, Bernardini C, Togninelli A, Carmi C, Alongi M, Petricci E, Massa S, Corelli F, Botta M. Manetti F, et al. Among authors: botta m. J Med Chem. 2005 Dec 15;48(25):8000-8. doi: 10.1021/jm050744t. J Med Chem. 2005. PMID: 16335924

5

Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.

Bondavalli F, Botta M, Bruno O, Ciacci A, Corelli F, Fossa P, Lucacchini A, Manetti F, Martini C, Menozzi G, Mosti L, Ranise A, Schenone S, Tafi A, Trincavellic ML. Bondavalli F, et al. Among authors: botta m. J Med Chem. 2002 Oct 24;45(22):4875-87. doi: 10.1021/jm0209580. J Med Chem. 2002. PMID: 12383013

6

Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models.

Tafi A, Bernardini C, Botta M, Corelli F, Andreini M, Martinelli A, Ortore G, Baraldi PG, Fruttarolo F, Borea PA, Tuccinardi T. Tafi A, et al. Among authors: botta m. J Med Chem. 2006 Jul 13;49(14):4085-97. doi: 10.1021/jm051112+. J Med Chem. 2006. PMID: 16821770

7

Alpha(1)-adrenoceptor antagonists. 4. Pharmacophore-based design, synthesis, and biological evaluation of new imidazo-, benzimidazo-, and indoloarylpiperazine derivatives.

Betti L, Botta M, Corelli F, Floridi M, Giannaccini G, Maccari L, Manetti F, Strappaghetti G, Tafi A, Corsano S. Betti L, et al. Among authors: botta m. J Med Chem. 2002 Aug 15;45(17):3603-11. doi: 10.1021/jm011077g. J Med Chem. 2002. PMID: 12166933

8

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs.

Radi M, Falciani C, Contemori L, Petricci E, Maga G, Samuele A, Zanoli S, Terrazas M, Castria M, Togninelli A, Esté JA, Clotet-Codina I, Armand-Ugón M, Botta M. Radi M, et al. Among authors: botta m. ChemMedChem. 2008 Apr;3(4):573-93. doi: 10.1002/cmdc.200700198. ChemMedChem. 2008. PMID: 18081133

9

Structure-activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A(3) adenosine receptor antagonists.

Baraldi PG, Preti D, Tabrizi MA, Romagnoli R, Saponaro G, Baraldi S, Botta M, Bernardini C, Tafi A, Tuccinardi T, Martinelli A, Varani K, Borea PA. Baraldi PG, et al. Among authors: botta m. Bioorg Med Chem. 2008 Dec 15;16(24):10281-94. doi: 10.1016/j.bmc.2008.10.049. Epub 2008 Nov 1. Bioorg Med Chem. 2008. PMID: 19006671

10

Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.

Manetti F, Schenone S, Bondavalli F, Brullo C, Bruno O, Ranise A, Mosti L, Menozzi G, Fossa P, Trincavelli ML, Martini C, Martinelli A, Tintori C, Botta M. Manetti F, et al. Among authors: botta m. J Med Chem. 2005 Nov 17;48(23):7172-85. doi: 10.1021/jm050407k. J Med Chem. 2005. PMID: 16279775

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