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Page 1
Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands.
Silvestri R, Ligresti A, La Regina G, Piscitelli F, Gatti V, Lavecchia A, Brizzi A, Pasquini S, Allarà M, Fantini N, Carai MA, Bigogno C, Rozio MG, Sinisi R, Novellino E, Colombo G, Di Marzo V, Dondio G, Corelli F. Silvestri R, et al. Among authors: gatti v. Eur J Med Chem. 2010 Dec;45(12):5878-86. doi: 10.1016/j.ejmech.2010.09.053. Epub 2010 Oct 1. Eur J Med Chem. 2010. PMID: 20943290
Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity profile.
Silvestri R, Ligresti A, La Regina G, Piscitelli F, Gatti V, Brizzi A, Pasquini S, Lavecchia A, Allarà M, Fantini N, Carai MA, Novellino E, Colombo G, Di Marzo V, Corelli F. Silvestri R, et al. Among authors: gatti v. Bioorg Med Chem. 2009 Aug 1;17(15):5549-64. doi: 10.1016/j.bmc.2009.06.027. Epub 2009 Jun 21. Bioorg Med Chem. 2009. PMID: 19595596
New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.
La Regina G, Sarkar T, Bai R, Edler MC, Saletti R, Coluccia A, Piscitelli F, Minelli L, Gatti V, Mazzoccoli C, Palermo V, Mazzoni C, Falcone C, Scovassi AI, Giansanti V, Campiglia P, Porta A, Maresca B, Hamel E, Brancale A, Novellino E, Silvestri R. La Regina G, et al. Among authors: gatti v. J Med Chem. 2009 Dec 10;52(23):7512-27. doi: 10.1021/jm900016t. J Med Chem. 2009. PMID: 19601594 Free PMC article.
Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.
La Regina G, Bai R, Rensen W, Coluccia A, Piscitelli F, Gatti V, Bolognesi A, Lavecchia A, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Mariani M, Santoni A, Brancale A, Ferlini C, Dondio G, Varasi M, Mercurio C, Hamel E, Lavia P, Novellino E, Silvestri R. La Regina G, et al. Among authors: gatti v. J Med Chem. 2011 Dec 22;54(24):8394-406. doi: 10.1021/jm2012886. Epub 2011 Nov 21. J Med Chem. 2011. PMID: 22044164 Free PMC article.
76 results