Darsigny M - Search Results

1

The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-Displacement-protein (CUX1) repressor.

Fréchette I, Darsigny M, Brochu-Gaudreau K, Jones C, Boudreau F. Fréchette I, et al. Among authors: darsigny m. FEBS J. 2010 Oct;277(20):4241-53. doi: 10.1111/j.1742-4658.2010.07813.x. FEBS J. 2010. PMID: 20945532 Free article.

2

Nuclear receptor co-repressor is required to maintain proliferation of normal intestinal epithelial cells in culture and down-modulates the expression of pigment epithelium-derived factor.

Doyon G, St-Jean S, Darsigny M, Asselin C, Boudreau F. Doyon G, et al. Among authors: darsigny m. J Biol Chem. 2009 Sep 11;284(37):25220-9. doi: 10.1074/jbc.M109.022632. Epub 2009 Jul 16. J Biol Chem. 2009. PMID: 19608741 Free PMC article.

3

Cux1 transcription factor is induced in inflammatory bowel disease and protects against experimental colitis.

Darsigny M, St-Jean S, Boudreau F. Darsigny M, et al. Inflamm Bowel Dis. 2010 Oct;16(10):1739-50. doi: 10.1002/ibd.21274. Inflamm Bowel Dis. 2010. PMID: 20848487

4

Transcription factor CUX1 is required for intestinal epithelial wound healing and targets the VAV2-RAC1 Signalling complex.

Latreille R, Servant R, Darsigny M, Marcoux S, Jones C, Perreault N, Boudreau F. Latreille R, et al. Among authors: darsigny m. Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2347-2355. doi: 10.1016/j.bbamcr.2017.09.005. Epub 2017 Sep 8. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28893557 Free article.

5

Hepatocyte nuclear factor 4alpha contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation.

Babeu JP, Darsigny M, Lussier CR, Boudreau F. Babeu JP, et al. Among authors: darsigny m. Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G124-34. doi: 10.1152/ajpgi.90690.2008. Epub 2009 Apr 23. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19389805 Free article.

6

Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.

Darsigny M, Babeu JP, Dupuis AA, Furth EE, Seidman EG, Lévy E, Verdu EF, Gendron FP, Boudreau F. Darsigny M, et al. PLoS One. 2009 Oct 29;4(10):e7609. doi: 10.1371/journal.pone.0007609. PLoS One. 2009. PMID: 19898610 Free PMC article.

7

Hepatocyte nuclear factor-4alpha promotes gut neoplasia in mice and protects against the production of reactive oxygen species.

Darsigny M, Babeu JP, Seidman EG, Gendron FP, Levy E, Carrier J, Perreault N, Boudreau F. Darsigny M, et al. Cancer Res. 2010 Nov 15;70(22):9423-33. doi: 10.1158/0008-5472.CAN-10-1697. Epub 2010 Nov 9. Cancer Res. 2010. PMID: 21062980

8

Loss of Smad5 leads to the disassembly of the apical junctional complex and increased susceptibility to experimental colitis.

Allaire JM, Darsigny M, Marcoux SS, Roy SA, Schmouth JF, Umans L, Zwijsen A, Boudreau F, Perreault N. Allaire JM, et al. Among authors: darsigny m. Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G586-97. doi: 10.1152/ajpgi.00041.2010. Epub 2011 Jan 6. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21212325 Free article.

9

Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia.

Boudreau F, Lussier CR, Mongrain S, Darsigny M, Drouin JL, Doyon G, Suh ER, Beaulieu JF, Rivard N, Perreault N. Boudreau F, et al. Among authors: darsigny m. FASEB J. 2007 Dec;21(14):3853-65. doi: 10.1096/fj.07-8113com. Epub 2007 Jul 10. FASEB J. 2007. PMID: 17622569

10

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.

Girard R, Darsigny M, Jones C, Maloum-Rami F, Gélinas Y, Carpentier AC, Laplante M, Perreault N, Boudreau F. Girard R, et al. Among authors: darsigny m. Sci Rep. 2019 Mar 12;9(1):4200. doi: 10.1038/s41598-019-41061-z. Sci Rep. 2019. PMID: 30862908 Free PMC article.

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