Alvarez LD - Search Results

1

Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.

Presman DM, Alvarez LD, Levi V, Eduardo S, Digman MA, Martí MA, Veleiro AS, Burton G, Pecci A. Presman DM, et al. Among authors: alvarez ld. PLoS One. 2010 Oct 11;5(10):e13279. doi: 10.1371/journal.pone.0013279. PLoS One. 2010. PMID: 20949009 Free PMC article.

2

Synthesis and GABA(A) receptor activity of oxygen-bridged neurosteroid analogs.

Alvarez LD, Veleiro AS, Baggio RF, Garland MT, Edelsztein VC, Coirini H, Burton G. Alvarez LD, et al. Bioorg Med Chem. 2008 Apr 1;16(7):3831-8. doi: 10.1016/j.bmc.2008.01.048. Epub 2008 Jan 30. Bioorg Med Chem. 2008. PMID: 18262792

3

Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone.

Alvarez LD, Martí MA, Veleiro AS, Presman DM, Estrin DA, Pecci A, Burton G. Alvarez LD, et al. J Med Chem. 2008 Mar 13;51(5):1352-60. doi: 10.1021/jm800007w. Epub 2008 Feb 20. J Med Chem. 2008. PMID: 18284186

4

Hemisuccinate of 21-hydroxy-6,19-epoxyprogesterone: a tissue-specific modulator of the glucocorticoid receptor.

Alvarez LD, Martí MA, Veleiro AS, Misico RI, Estrin DA, Pecci A, Burton G. Alvarez LD, et al. ChemMedChem. 2008 Dec;3(12):1869-77. doi: 10.1002/cmdc.200800256. ChemMedChem. 2008. PMID: 18985652

5

New lead compounds in the search for pure antiglucocorticoids and the dissociation of antiglucocorticoid effects.

Pecci A, Alvarez LD, Veleiro AS, Ceballos NR, Lantos CP, Burton G. Pecci A, et al. Among authors: alvarez ld. J Steroid Biochem Mol Biol. 2009 Feb;113(3-5):155-62. doi: 10.1016/j.jsbmb.2008.12.018. Epub 2009 Jan 9. J Steroid Biochem Mol Biol. 2009. PMID: 19167494 Review.

6

Structure of the glucocorticoid receptor, a flexible protein that can adapt to different ligands.

Veleiro AS, Alvarez LD, Eduardo SL, Burton G. Veleiro AS, et al. Among authors: alvarez ld. ChemMedChem. 2010 May 3;5(5):649-59. doi: 10.1002/cmdc.201000014. ChemMedChem. 2010. PMID: 20333619 Review. No abstract available.

7

Biological activity and ligand binding mode to the progesterone receptor of A-homo analogues of progesterone.

Alvarez LD, Dansey MV, Martí MA, Bertucci PY, Di Chenna PH, Pecci A, Burton G. Alvarez LD, et al. Bioorg Med Chem. 2011 Mar 1;19(5):1683-91. doi: 10.1016/j.bmc.2011.01.033. Epub 2011 Jan 22. Bioorg Med Chem. 2011. PMID: 21315613

8

Microwave assisted preparation of C1-C11 oxygen-bridged pregnanes.

Alvarez LD, Sonego JM, Veleiro AS, Burton G. Alvarez LD, et al. Steroids. 2011 Dec 11;76(13):1458-64. doi: 10.1016/j.steroids.2011.07.016. Epub 2011 Aug 9. Steroids. 2011. PMID: 21846475

9

The Caenorhabditis elegans DAF-12 nuclear receptor: structure, dynamics, and interaction with ligands.

Alvarez LD, Mañez PA, Estrin DA, Burton G. Alvarez LD, et al. Proteins. 2012 Jul;80(7):1798-809. doi: 10.1002/prot.24076. Epub 2012 May 10. Proteins. 2012. PMID: 22489014

10

27-Nor-Δ(4)-dafachronic acid is a synthetic ligand of Caenorhabditis elegans DAF-12 receptor.

Samaja GA, Castro O, Alvarez LD, Dansey MV, Escudero DS, Veleiro AS, Pecci A, Burton G. Samaja GA, et al. Among authors: alvarez ld. Bioorg Med Chem Lett. 2013 May 15;23(10):2893-6. doi: 10.1016/j.bmcl.2013.03.071. Epub 2013 Mar 28. Bioorg Med Chem Lett. 2013. PMID: 23570785

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