Fledderus JO - Search Results

1

Activin A induces a non-fibrotic phenotype in smooth muscle cells in contrast to TGF-β.

Groenendijk BC, Benus GF, Klous A, Pacheco YM, Volger OL, Fledderus JO, Ferreira V, Engelse MA, Pannekoek H, ten Dijke P, Horrevoets AJ, de Vries CJ. Groenendijk BC, et al. Among authors: fledderus jo. Exp Cell Res. 2011 Jan 15;317(2):131-42. doi: 10.1016/j.yexcr.2010.10.007. Epub 2010 Oct 15. Exp Cell Res. 2011. PMID: 20955695

2

KLF2 suppresses TGF-beta signaling in endothelium through induction of Smad7 and inhibition of AP-1.

Boon RA, Fledderus JO, Volger OL, van Wanrooij EJ, Pardali E, Weesie F, Kuiper J, Pannekoek H, ten Dijke P, Horrevoets AJ. Boon RA, et al. Among authors: fledderus jo. Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):532-9. doi: 10.1161/01.ATV.0000256466.65450.ce. Epub 2006 Dec 28. Arterioscler Thromb Vasc Biol. 2007. PMID: 17194892

3

Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization.

van Thienen JV, Fledderus JO, Dekker RJ, Rohlena J, van Ijzendoorn GA, Kootstra NA, Pannekoek H, Horrevoets AJ. van Thienen JV, et al. Among authors: fledderus jo. Cardiovasc Res. 2006 Nov 1;72(2):231-40. doi: 10.1016/j.cardiores.2006.07.008. Epub 2006 Jul 12. Cardiovasc Res. 2006. PMID: 16945356

4

Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2.

Fledderus JO, van Thienen JV, Boon RA, Dekker RJ, Rohlena J, Volger OL, Bijnens AP, Daemen MJ, Kuiper J, van Berkel TJ, Pannekoek H, Horrevoets AJ. Fledderus JO, et al. Blood. 2007 May 15;109(10):4249-57. doi: 10.1182/blood-2006-07-036020. Epub 2007 Jan 23. Blood. 2007. PMID: 17244683 Free article.

5

Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis.

Volger OL, Fledderus JO, Kisters N, Fontijn RD, Moerland PD, Kuiper J, van Berkel TJ, Bijnens AP, Daemen MJ, Pannekoek H, Horrevoets AJ. Volger OL, et al. Among authors: fledderus jo. Am J Pathol. 2007 Jul;171(1):326-37. doi: 10.2353/ajpath.2007.061196. Am J Pathol. 2007. PMID: 17591977 Free PMC article.

6

SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function.

Fontijn RD, Volger OL, Fledderus JO, Reijerkerk A, de Vries HE, Horrevoets AJ. Fontijn RD, et al. Among authors: fledderus jo. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H891-900. doi: 10.1152/ajpheart.01248.2007. Epub 2007 Dec 7. Am J Physiol Heart Circ Physiol. 2008. PMID: 18065521 Free article.

7

KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells.

Fledderus JO, Boon RA, Volger OL, Hurttila H, Ylä-Herttuala S, Pannekoek H, Levonen AL, Horrevoets AJ. Fledderus JO, et al. Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1339-46. doi: 10.1161/ATVBAHA.108.165811. Epub 2008 May 8. Arterioscler Thromb Vasc Biol. 2008. PMID: 18467642

8

KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium.

Boon RA, Leyen TA, Fontijn RD, Fledderus JO, Baggen JM, Volger OL, van Nieuw Amerongen GP, Horrevoets AJ. Boon RA, et al. Among authors: fledderus jo. Blood. 2010 Mar 25;115(12):2533-42. doi: 10.1182/blood-2009-06-228726. Epub 2009 Dec 23. Blood. 2010. PMID: 20032497 Free article.

9

Interferon-beta signaling is enhanced in patients with insufficient coronary collateral artery development and inhibits arteriogenesis in mice.

Schirmer SH, Fledderus JO, Bot PT, Moerland PD, Hoefer IE, Baan J Jr, Henriques JP, van der Schaaf RJ, Vis MM, Horrevoets AJ, Piek JJ, van Royen N. Schirmer SH, et al. Among authors: fledderus jo. Circ Res. 2008 May 23;102(10):1286-94. doi: 10.1161/CIRCRESAHA.108.171827. Epub 2008 Apr 17. Circ Res. 2008. PMID: 18420941

10

Suppression of inflammatory signaling in monocytes from patients with coronary artery disease.

Schirmer SH, Fledderus JO, van der Laan AM, van der Pouw-Kraan TC, Moerland PD, Volger OL, Baggen JM, Böhm M, Piek JJ, Horrevoets AJ, van Royen N. Schirmer SH, et al. Among authors: fledderus jo. J Mol Cell Cardiol. 2009 Feb;46(2):177-85. doi: 10.1016/j.yjmcc.2008.10.029. Epub 2008 Nov 14. J Mol Cell Cardiol. 2009. PMID: 19059264

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