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Regulation of mammalian autophagy in physiology and pathophysiology.
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Moreau K, Narayanan U, Renna M, Siddiqi FH, Underwood BR, Winslow AR, Rubinsztein DC. Ravikumar B, et al. Physiol Rev. 2010 Oct;90(4):1383-435. doi: 10.1152/physrev.00030.2009. Physiol Rev. 2010. PMID: 20959619 Free article. Review.
Autophagy, a guardian against neurodegeneration.
García-Arencibia M, Hochfeld WE, Toh PP, Rubinsztein DC. García-Arencibia M, et al. Semin Cell Dev Biol. 2010 Sep;21(7):691-8. doi: 10.1016/j.semcdb.2010.02.008. Epub 2010 Feb 24. Semin Cell Dev Biol. 2010. PMID: 20188203 Free PMC article. Review.
Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.
Menzies FM, Garcia-Arencibia M, Imarisio S, O'Sullivan NC, Ricketts T, Kent BA, Rao MV, Lam W, Green-Thompson ZW, Nixon RA, Saksida LM, Bussey TJ, O'Kane CJ, Rubinsztein DC. Menzies FM, et al. Among authors: garcia arencibia m. Cell Death Differ. 2015 Mar;22(3):433-44. doi: 10.1038/cdd.2014.151. Epub 2014 Sep 26. Cell Death Differ. 2015. PMID: 25257175 Free PMC article.
Autophagy and misfolded proteins in neurodegeneration.
Metcalf DJ, García-Arencibia M, Hochfeld WE, Rubinsztein DC. Metcalf DJ, et al. Exp Neurol. 2012 Nov;238(1):22-8. doi: 10.1016/j.expneurol.2010.11.003. Epub 2010 Nov 21. Exp Neurol. 2012. PMID: 21095248 Free PMC article. Review.
Complex inhibitory effects of nitric oxide on autophagy.
Sarkar S, Korolchuk VI, Renna M, Imarisio S, Fleming A, Williams A, Garcia-Arencibia M, Rose C, Luo S, Underwood BR, Kroemer G, O'Kane CJ, Rubinsztein DC. Sarkar S, et al. Mol Cell. 2011 Jul 8;43(1):19-32. doi: 10.1016/j.molcel.2011.04.029. Mol Cell. 2011. PMID: 21726807 Free PMC article.
IGF-1 receptor antagonism inhibits autophagy.
Renna M, Bento CF, Fleming A, Menzies FM, Siddiqi FH, Ravikumar B, Puri C, Garcia-Arencibia M, Sadiq O, Corrochano S, Carter S, Brown SD, Acevedo-Arozena A, Rubinsztein DC. Renna M, et al. Hum Mol Genet. 2013 Nov 15;22(22):4528-44. doi: 10.1093/hmg/ddt300. Epub 2013 Jun 25. Hum Mol Genet. 2013. PMID: 23804751 Free PMC article.
Bim inhibits autophagy by recruiting Beclin 1 to microtubules.
Luo S, Garcia-Arencibia M, Zhao R, Puri C, Toh PP, Sadiq O, Rubinsztein DC. Luo S, et al. Mol Cell. 2012 Aug 10;47(3):359-70. doi: 10.1016/j.molcel.2012.05.040. Epub 2012 Jun 27. Mol Cell. 2012. PMID: 22742832 Free PMC article.
TFEB links autophagy to lysosomal biogenesis.
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, Sardiello M, Rubinsztein DC, Ballabio A. Settembre C, et al. Science. 2011 Jun 17;332(6036):1429-33. doi: 10.1126/science.1204592. Epub 2011 May 26. Science. 2011. PMID: 21617040 Free PMC article.
Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
van Ham TJ, Holmberg MA, van der Goot AT, Teuling E, Garcia-Arencibia M, Kim HE, Du D, Thijssen KL, Wiersma M, Burggraaff R, van Bergeijk P, van Rheenen J, Jerre van Veluw G, Hofstra RM, Rubinsztein DC, Nollen EA. van Ham TJ, et al. Cell. 2010 Aug 20;142(4):601-12. doi: 10.1016/j.cell.2010.07.020. Cell. 2010. PMID: 20723760 Free article.
36 results