Wünsch B - Search Results

1

Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.

Tewes B, Frehland B, Schepmann D, Schmidtke KU, Winckler T, Wünsch B. Tewes B, et al. Among authors: wunsch b. Bioorg Med Chem. 2010 Nov 15;18(22):8005-15. doi: 10.1016/j.bmc.2010.09.026. Epub 2010 Sep 24. Bioorg Med Chem. 2010. PMID: 20965739

2

Noncompetitive NMDA antagonists: a novel synthesis of 1-phenyltetrahydro-3-benzazepines.

Wünsch B, Nerdinger S, Bauschke G, Höfner G. Wünsch B, et al. Arch Pharm (Weinheim). 1997 Jul;330(7):211-4. doi: 10.1002/ardp.19973300705. Arch Pharm (Weinheim). 1997. PMID: 9311300

3

Stereoselective synthesis and receptor binding of conformationally restricted and flexible 2,4-disubstituted 1,3-dioxanes derived from benzomorphans.

Wünsch B, Bauschke G, Diekmann H, Höfner G. Wünsch B, et al. Arch Pharm (Weinheim). 1999 Dec;332(12):413-21. doi: 10.1002/(sici)1521-4184(199912)332:12<413::aid-ardp413>3.0.co;2-0. Arch Pharm (Weinheim). 1999. PMID: 10634091

4

Synthesis and stereoselective kappa-receptor binding of methylated analogues of GR-89.696.

Röhr C, Soukara S, Wünsch B. Röhr C, et al. Among authors: wunsch b. Eur J Med Chem. 2001 Feb;36(2):211-4. doi: 10.1016/s0223-5234(00)01208-3. Eur J Med Chem. 2001. PMID: 11311752

5

Methylated analogues of methyl (R)-4-(3,4-dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as highly potent kappa-receptor agonists: stereoselective synthesis, opioid-receptor affinity, receptor selectivity, and functional studies.

Soukara S, Maier CA, Predoiu U, Ehret A, Jackisch R, Wünsch B. Soukara S, et al. Among authors: wunsch b. J Med Chem. 2001 Aug 16;44(17):2814-26. doi: 10.1021/jm0108395. J Med Chem. 2001. PMID: 11495592

6

Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1.

Maier CA, Wünsch B. Maier CA, et al. Among authors: wunsch b. J Med Chem. 2002 Jan 17;45(2):438-48. doi: 10.1021/jm010992z. J Med Chem. 2002. PMID: 11784148

7

Conformationally constrained ethylenediamines: synthesis and receptor binding of 6,8-diazabicyclo[3.2.2]nonanes.

Weigl M, Bedürftig S, Maier CA, Wünsch B. Weigl M, et al. Among authors: wunsch b. Bioorg Med Chem. 2002 Jul;10(7):2245-57. doi: 10.1016/s0968-0896(02)00043-3. Bioorg Med Chem. 2002. PMID: 11983522

8

Novel sigma receptor ligands. Part 2. SAR of spiro[[2]benzopyran-1,4'-piperidines] and spiro[[2]benzofuran-1,4'-piperidines] with carbon substituents in position 3.

Maier CA, Wünsch B. Maier CA, et al. Among authors: wunsch b. J Med Chem. 2002 Oct 24;45(22):4923-30. doi: 10.1021/jm020889p. J Med Chem. 2002. PMID: 12383018

9

Synthesis and NMDA-receptor affinity of ring and side chain homologous dexoxadrol derivatives.

Aepkers M, Wünsch B. Aepkers M, et al. Among authors: wunsch b. Arch Pharm (Weinheim). 2004 Feb;337(2):67-75. doi: 10.1002/ardp.200300821. Arch Pharm (Weinheim). 2004. PMID: 14981662

10

Synthesis and structure/NMDA receptor affinity relationships of 1-substituted tetrahydro-3-benzazepines.

Krull O, Wünsch B. Krull O, et al. Among authors: wunsch b. Bioorg Med Chem. 2004 Mar 15;12(6):1439-51. doi: 10.1016/j.bmc.2003.12.036. Bioorg Med Chem. 2004. PMID: 15018917

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