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Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus.
Merchant M, Evangelista M, Luoh SM, Frantz GD, Chalasani S, Carano RA, van Hoy M, Ramirez J, Ogasawara AK, McFarland LM, Filvaroff EH, French DM, de Sauvage FJ. Merchant M, et al. Among authors: de sauvage fj. Mol Cell Biol. 2005 Aug;25(16):7054-68. doi: 10.1128/MCB.25.16.7054-7068.2005. Mol Cell Biol. 2005. PMID: 16055717 Free PMC article.
The hedgehog signaling pathway in cancer.
Evangelista M, Tian H, de Sauvage FJ. Evangelista M, et al. Among authors: de sauvage fj. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):5924-8. doi: 10.1158/1078-0432.CCR-06-1736. Clin Cancer Res. 2006. PMID: 17062662 Review.
A paracrine requirement for hedgehog signalling in cancer.
Yauch RL, Gould SE, Scales SJ, Tang T, Tian H, Ahn CP, Marshall D, Fu L, Januario T, Kallop D, Nannini-Pepe M, Kotkow K, Marsters JC, Rubin LL, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Nature. 2008 Sep 18;455(7211):406-10. doi: 10.1038/nature07275. Epub 2008 Aug 27. Nature. 2008. PMID: 18754008
Paracrine Hedgehog signaling in cancer.
Theunissen JW, de Sauvage FJ. Theunissen JW, et al. Among authors: de sauvage fj. Cancer Res. 2009 Aug 1;69(15):6007-10. doi: 10.1158/0008-5472.CAN-09-0756. Epub 2009 Jul 28. Cancer Res. 2009. PMID: 19638582 Review.
Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.
Yauch RL, Dijkgraaf GJ, Alicke B, Januario T, Ahn CP, Holcomb T, Pujara K, Stinson J, Callahan CA, Tang T, Bazan JF, Kan Z, Seshagiri S, Hann CL, Gould SE, Low JA, Rudin CM, de Sauvage FJ. Yauch RL, et al. Among authors: de sauvage fj. Science. 2009 Oct 23;326(5952):572-4. doi: 10.1126/science.1179386. Epub 2009 Sep 2. Science. 2009. PMID: 19726788 Free PMC article.
185 results