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Beating the odds: BETs in disease.
Wang CY, Filippakopoulos P. Wang CY, et al. Among authors: filippakopoulos p. Trends Biochem Sci. 2015 Aug;40(8):468-79. doi: 10.1016/j.tibs.2015.06.002. Epub 2015 Jul 3. Trends Biochem Sci. 2015. PMID: 26145250 Review.
Structure and functional characterization of the atypical human kinase haspin.
Eswaran J, Patnaik D, Filippakopoulos P, Wang F, Stein RL, Murray JW, Higgins JM, Knapp S. Eswaran J, et al. Among authors: filippakopoulos p. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20198-203. doi: 10.1073/pnas.0901989106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918057 Free PMC article.
Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space.
Piticchio SG, Martínez-Cartró M, Scaffidi S, Rachman M, Rodriguez-Arevalo S, Sanchez-Arfelis A, Escolano C, Picaud S, Krojer T, Filippakopoulos P, von Delft F, Galdeano C, Barril X. Piticchio SG, et al. Among authors: filippakopoulos p. J Med Chem. 2021 Dec 23;64(24):17887-17900. doi: 10.1021/acs.jmedchem.1c01108. Epub 2021 Dec 13. J Med Chem. 2021. PMID: 34898210
Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Chen Z, Picaud S, Filippakopoulos P, D'Angiolella V, Bullock AN. Chen Z, et al. Among authors: filippakopoulos p. Structure. 2019 Sep 3;27(9):1395-1404.e4. doi: 10.1016/j.str.2019.06.005. Epub 2019 Jul 3. Structure. 2019. PMID: 31279627 Free PMC article.
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.
Savitsky P, Krojer T, Fujisawa T, Lambert JP, Picaud S, Wang CY, Shanle EK, Krajewski K, Friedrichsen H, Kanapin A, Goding C, Schapira M, Samsonova A, Strahl BD, Gingras AC, Filippakopoulos P. Savitsky P, et al. Among authors: filippakopoulos p. Cell Rep. 2016 Dec 6;17(10):2724-2737. doi: 10.1016/j.celrep.2016.11.014. Cell Rep. 2016. PMID: 27926874 Free PMC article.
96 results